Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ-RelB
Location 400438..401009 Replicon chromosome
Accession NZ_CP123050
Organism Bifidobacterium adolescentis strain iVS-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QEP23_RS01540 Protein ID WP_003807675.1
Coordinates 400438..400737 (-) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0C2Z6P7
Locus tag QEP23_RS01545 Protein ID WP_034984155.1
Coordinates 400737..401009 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEP23_RS01530 (QEP23_01530) 397133..397861 + 729 WP_042989841.1 type 1 glutamine amidotransferase -
QEP23_RS01535 (QEP23_01535) 398173..400341 + 2169 WP_042989842.1 ABC-F family ATP-binding cassette domain-containing protein -
QEP23_RS01540 (QEP23_01540) 400438..400737 - 300 WP_003807675.1 type II toxin-antitoxin system YafQ family toxin Toxin
QEP23_RS01545 (QEP23_01545) 400737..401009 - 273 WP_034984155.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
QEP23_RS01550 (QEP23_01550) 401123..401959 - 837 WP_042989843.1 hypothetical protein -
QEP23_RS01555 (QEP23_01555) 402143..402682 + 540 WP_003807679.1 hypothetical protein -
QEP23_RS01560 (QEP23_01560) 402675..403193 + 519 WP_130082043.1 hypothetical protein -
QEP23_RS01565 (QEP23_01565) 403252..404406 - 1155 WP_046998989.1 ATP-binding protein -
QEP23_RS01570 (QEP23_01570) 404409..405038 - 630 WP_003807685.1 response regulator transcription factor -
QEP23_RS01575 (QEP23_01575) 405205..405816 + 612 WP_236836162.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-98)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-69)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11662.09 Da        Isoelectric Point: 8.0955

>T278598 WP_003807675.1 NZ_CP123050:c400737-400438 [Bifidobacterium adolescentis]
MGRLTADFAKAFSRDLKKNAKRRNWNLTELEKVIDLVVENTPETLEELRRRHNMHTLSGNWRGRYECHVANAGDWLVIWS
SNDSVAFFERTGSHDELFR

Download         Length: 300 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9714.91 Da        Isoelectric Point: 4.5535

>AT278598 WP_034984155.1 NZ_CP123050:c401009-400737 [Bifidobacterium adolescentis]
MSASTLTIRMDDELKRSAADVAEYYGLDLSSVVRAVFKQMVNTGRIPLTFAPEEPNGESLNAAAEADSFMASGKTGRFTN
GHDLLEAAMR

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0C2Z6P7

References