Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/Cpta(toxin) |
Location | 856756..857413 | Replicon | chromosome |
Accession | NZ_CP123043 | ||
Organism | Klebsiella pneumoniae strain KP161637 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | W8UCT0 |
Locus tag | QDF61_RS04330 | Protein ID | WP_002916310.1 |
Coordinates | 857003..857413 (+) | Length | 137 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | W8UQ37 |
Locus tag | QDF61_RS04325 | Protein ID | WP_002916312.1 |
Coordinates | 856756..857022 (+) | Length | 89 a.a. |
Genomic Context
Location: 854242..854553 (312 bp)
Type: Others
Protein ID: WP_004144734.1
Type: Others
Protein ID: WP_004144734.1
Location: 854717..855376 (660 bp)
Type: Others
Protein ID: WP_002916317.1
Type: Others
Protein ID: WP_002916317.1
Location: 856756..857022 (267 bp)
Type: Antitoxin
Protein ID: WP_002916312.1
Type: Antitoxin
Protein ID: WP_002916312.1
Location: 857003..857413 (411 bp)
Type: Toxin
Protein ID: WP_002916310.1
Type: Toxin
Protein ID: WP_002916310.1
Location: 858042..858938 (897 bp)
Type: Others
Protein ID: WP_004144729.1
Type: Others
Protein ID: WP_004144729.1
Location: 858961..859674 (714 bp)
Type: Others
Protein ID: WP_002916301.1
Type: Others
Protein ID: WP_002916301.1
Location: 859680..861413 (1734 bp)
Type: Others
Protein ID: WP_004149758.1
Type: Others
Protein ID: WP_004149758.1
Location: 851912..853345 (1434 bp)
Type: Others
Protein ID: WP_002916322.1
Type: Others
Protein ID: WP_002916322.1
Location: 853464..854192 (729 bp)
Type: Others
Protein ID: WP_002916321.1
Type: Others
Protein ID: WP_002916321.1
Location: 855527..856510 (984 bp)
Type: Others
Protein ID: WP_002916313.1
Type: Others
Protein ID: WP_002916313.1
Location: 857420..857941 (522 bp)
Type: Others
Protein ID: WP_002916308.1
Type: Others
Protein ID: WP_002916308.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QDF61_RS04300 (851912) | 851912..853345 | - | 1434 | WP_002916322.1 | 6-phospho-beta-glucosidase BglA | - |
QDF61_RS04305 (853464) | 853464..854192 | - | 729 | WP_002916321.1 | MurR/RpiR family transcriptional regulator | - |
QDF61_RS04310 (854242) | 854242..854553 | + | 312 | WP_004144734.1 | N(4)-acetylcytidine aminohydrolase | - |
QDF61_RS04315 (854717) | 854717..855376 | + | 660 | WP_002916317.1 | hemolysin III family protein | - |
QDF61_RS04320 (855527) | 855527..856510 | - | 984 | WP_002916313.1 | tRNA-modifying protein YgfZ | - |
QDF61_RS04325 (856756) | 856756..857022 | + | 267 | WP_002916312.1 | FAD assembly factor SdhE | Antitoxin |
QDF61_RS04330 (857003) | 857003..857413 | + | 411 | WP_002916310.1 | protein YgfX | Toxin |
QDF61_RS04335 (857420) | 857420..857941 | - | 522 | WP_002916308.1 | flavodoxin FldB | - |
QDF61_RS04340 (858042) | 858042..858938 | + | 897 | WP_004144729.1 | site-specific tyrosine recombinase XerD | - |
QDF61_RS04345 (858961) | 858961..859674 | + | 714 | WP_002916301.1 | bifunctional protein-disulfide isomerase/oxidoreductase DsbC | - |
QDF61_RS04350 (859680) | 859680..861413 | + | 1734 | WP_004149758.1 | single-stranded-DNA-specific exonuclease RecJ | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 137 a.a. Molecular weight: 16049.85 Da Isoelectric Point: 11.4778
>T278553 WP_002916310.1 NZ_CP123043:857003-857413 [Klebsiella pneumoniae]
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE
VVLWQSDLRISWRAQWFSLLLHGVVAALVLLVPWPLSYTPIWLLLLSLVVFDCVRSQRRIHARRGEIKLLTDSRLRWQNA
EWEILGTPWVINSGMLLRLRHVDTRRGQHLWLAADSMDAGEWRDLRRLVLQKPAQE
Download Length: 411 bp
Antitoxin
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3GSW7 |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0H3GY41 |