Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1990323..1990468 Replicon chromosome
Accession NZ_CP123040
Organism Klebsiella pneumoniae strain KP160802

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1990359..1990461 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1990323..1990468 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDE57_RS09670 1985453..1987513 + 2061 WP_004151449.1 oligopeptidase B -
QDE57_RS09675 1987517..1988176 - 660 WP_002911407.1 exodeoxyribonuclease X -
QDE57_RS09680 1988255..1988485 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QDE57_RS09685 1988598..1988972 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QDE57_RS09690 1988976..1989845 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
QDE57_RS09695 1989862..1990200 + 339 WP_016529031.1 YebY family protein -
- 1990323..1990468 - 146 - - Antitoxin
- 1990359..1990461 + 103 - - Toxin
QDE57_RS09700 1990836..1990979 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QDE57_RS09705 1991084..1992052 - 969 WP_004151446.1 VirK/YbjX family protein -
QDE57_RS09710 1992209..1992862 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
QDE57_RS09715 1992859..1993050 - 192 WP_002911395.1 YebW family protein -
QDE57_RS09720 1993148..1993387 - 240 WP_002911393.1 YebV family protein -
QDE57_RS09725 1993503..1994936 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T278540 NZ_CP123040:1990359-1990461 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT278540 NZ_CP123040:c1990468-1990323 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References