Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2100845..2101116 Replicon chromosome
Accession NZ_CP123036
Organism Escherichia coli strain E22

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2100975..2101078 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2100845..2101116 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN54_RS10155 2097400..2098062 - 663 WP_000944256.1 exodeoxyribonuclease X -
QEN54_RS10160 2098086..2098742 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QEN54_RS10165 2098844..2099074 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QEN54_RS10170 2099213..2099587 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QEN54_RS10175 2099591..2100463 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
QEN54_RS10180 2100476..2100817 + 342 WP_000976492.1 YebY family protein -
- 2100845..2101116 - 272 - - Antitoxin
- 2100975..2101078 + 104 - - Toxin
QEN54_RS10185 2101213..2101869 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QEN54_RS10190 2101870..2102061 - 192 WP_001296140.1 YebW family protein -
QEN54_RS10195 2102166..2102402 - 237 WP_001295499.1 YebV family protein -
QEN54_RS10200 2102520..2103959 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278522 NZ_CP123036:2100975-2101078 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT278522 NZ_CP123036:c2101116-2100845 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References