Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2101666..2101937 Replicon chromosome
Accession NZ_CP123024
Organism Escherichia coli strain 20-16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2101796..2101899 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2101666..2101937 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN53_RS10160 2098221..2098883 - 663 WP_000944256.1 exodeoxyribonuclease X -
QEN53_RS10165 2098907..2099563 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QEN53_RS10170 2099665..2099895 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QEN53_RS10175 2100034..2100408 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QEN53_RS10180 2100412..2101284 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
QEN53_RS10185 2101297..2101638 + 342 WP_000976492.1 YebY family protein -
- 2101666..2101937 - 272 - - Antitoxin
- 2101796..2101899 + 104 - - Toxin
QEN53_RS10190 2102034..2102690 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QEN53_RS10195 2102691..2102882 - 192 WP_001296140.1 YebW family protein -
QEN53_RS10200 2102987..2103223 - 237 WP_001295499.1 YebV family protein -
QEN53_RS10205 2103341..2104780 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2058753..2117775 59022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278470 NZ_CP123024:2101796-2101899 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT278470 NZ_CP123024:c2101937-2101666 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References