Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2104969..2105240 Replicon chromosome
Accession NZ_CP123013
Organism Escherichia coli strain 18-4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2105099..2105202 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2104969..2105240 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEN56_RS10175 2101524..2102186 - 663 WP_000944256.1 exodeoxyribonuclease X -
QEN56_RS10180 2102210..2102866 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QEN56_RS10185 2102968..2103198 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QEN56_RS10190 2103337..2103711 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QEN56_RS10195 2103715..2104587 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
QEN56_RS10200 2104600..2104941 + 342 WP_000976492.1 YebY family protein -
- 2104969..2105240 - 272 - - Antitoxin
- 2105099..2105202 + 104 - - Toxin
QEN56_RS10205 2105337..2105993 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QEN56_RS10210 2105994..2106185 - 192 WP_001296140.1 YebW family protein -
QEN56_RS10215 2106290..2106526 - 237 WP_001295499.1 YebV family protein -
QEN56_RS10220 2106644..2108083 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2062056..2121078 59022


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278418 NZ_CP123013:2105099-2105202 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT278418 NZ_CP123013:c2105240-2104969 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References