Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | phd-doc/HTH_IclR(antitoxin) |
Location | 5852080..5853788 | Replicon | chromosome |
Accession | NC_017911 | ||
Organism | Pseudomonas fluorescens A506 |
Toxin (Protein)
Gene name | doc | Uniprot ID | - |
Locus tag | PFLA506_RS26420 | Protein ID | WP_014720526.1 |
Coordinates | 5852080..5852958 (+) | Length | 293 a.a. |
Antitoxin (Protein)
Gene name | phd | Uniprot ID | - |
Locus tag | PFLA506_RS26425 | Protein ID | WP_003195671.1 |
Coordinates | 5852955..5853788 (+) | Length | 278 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PFLA506_RS26395 | 5848071..5848922 | + | 852 | WP_003195659.1 | ABC transporter ATP-binding protein | - |
PFLA506_RS26400 | 5848962..5849954 | + | 993 | WP_014720522.1 | ABC transporter substrate-binding protein | - |
PFLA506_RS26405 | 5849982..5850758 | + | 777 | WP_014720523.1 | ABC transporter permease | - |
PFLA506_RS26410 | 5850758..5851522 | + | 765 | WP_044483644.1 | SDR family oxidoreductase | - |
PFLA506_RS26415 | 5851536..5852075 | + | 540 | WP_014720525.1 | cupin domain-containing protein | - |
PFLA506_RS26420 | 5852080..5852958 | + | 879 | WP_014720526.1 | alpha/beta hydrolase | Toxin |
PFLA506_RS26425 | 5852955..5853788 | + | 834 | WP_003195671.1 | IclR family transcriptional regulator | Antitoxin |
PFLA506_RS26430 | 5853790..5854587 | + | 798 | WP_014720527.1 | SDR family oxidoreductase | - |
PFLA506_RS26435 | 5854580..5856265 | + | 1686 | WP_044483532.1 | thiamine pyrophosphate-binding protein | - |
PFLA506_RS26440 | 5856276..5857088 | + | 813 | WP_014720529.1 | aspartate dehydrogenase | - |
PFLA506_RS26445 | 5857098..5858594 | + | 1497 | WP_014720530.1 | aldehyde dehydrogenase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 293 a.a. Molecular weight: 30890.34 Da Isoelectric Point: 7.6898
>T27837 WP_014720526.1 NC_017911:5852080-5852958 [Pseudomonas fluorescens A506]
MLPGLSQAAPTADLQAQLERDFPQRLVAAAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLATQARVIAWDAPGYG
DSSALESDVPKAEQYAARLAQMLDALEVETFVLVGHSLGALTALAFARSSQAHRVSRLVLISPARGYGAPQLAQRRQQVR
QQRLDNLQRLGIAGLAEQRSAHMLSPRATPQALAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACALQQSLTGTTL
MLPGLSQAAPTADLQAQLERDFPQRLVAAAGGQQALRECGAGPVVVLLHGIGSGAASWLQVARQLATQARVIAWDAPGYG
DSSALESDVPKAEQYAARLAQMLDALEVETFVLVGHSLGALTALAFARSSQAHRVSRLVLISPARGYGAPQLAQRRQQVR
QQRLDNLQRLGIAGLAEQRSAHMLSPRATPQALAWVRWNMARLNPVGYRQAIELLCGDDLLRHGQPAMPCEVHCGEADSI
TPAEACLSVAKALGASFNLIADAGHASPIEQPQVVAGRLACALQQSLTGTTL
Download Length: 879 bp
>T27837 NC_017911:5852080-5852958 [Pseudomonas fluorescens A506]
ATGCTGCCAGGACTTTCTCAAGCCGCGCCGACGGCCGACCTGCAAGCCCAACTGGAGCGTGATTTTCCTCAGCGCCTGGT
GGCTGCAGCCGGAGGGCAACAGGCCTTGCGCGAATGCGGCGCGGGGCCAGTGGTGGTGTTGCTGCACGGTATCGGCTCCG
GAGCGGCGTCCTGGCTGCAAGTGGCTCGGCAACTGGCAACCCAGGCCCGGGTCATTGCGTGGGATGCACCCGGCTACGGC
GACTCCAGTGCACTGGAGTCGGACGTTCCCAAGGCTGAGCAGTACGCAGCACGTTTGGCACAGATGCTCGATGCATTGGA
GGTCGAAACCTTCGTGCTGGTGGGTCACTCACTGGGAGCCCTCACCGCCCTGGCGTTCGCCCGCAGTTCGCAGGCCCATC
GGGTGAGCCGCCTGGTGTTGATCAGCCCGGCTCGCGGTTATGGCGCACCGCAGCTGGCCCAACGGCGCCAACAGGTACGC
CAGCAGCGCCTGGACAACCTGCAACGTCTGGGTATCGCCGGCCTGGCCGAACAACGCAGCGCTCACATGTTGTCGCCGCG
TGCCACGCCCCAGGCCCTGGCCTGGGTGCGTTGGAACATGGCACGCCTGAACCCCGTCGGTTATCGCCAGGCGATTGAAT
TGCTGTGCGGCGATGACCTGCTGCGCCATGGCCAGCCGGCCATGCCCTGCGAGGTGCATTGCGGTGAAGCCGACAGCATC
ACCCCCGCCGAGGCCTGCCTGAGCGTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATCGCCGACGCCGGCCACGCCAG
CCCCATCGAACAACCCCAAGTGGTTGCCGGGCGCCTGGCCTGTGCCCTCCAACAATCCCTGACAGGTACAACCCTATGA
ATGCTGCCAGGACTTTCTCAAGCCGCGCCGACGGCCGACCTGCAAGCCCAACTGGAGCGTGATTTTCCTCAGCGCCTGGT
GGCTGCAGCCGGAGGGCAACAGGCCTTGCGCGAATGCGGCGCGGGGCCAGTGGTGGTGTTGCTGCACGGTATCGGCTCCG
GAGCGGCGTCCTGGCTGCAAGTGGCTCGGCAACTGGCAACCCAGGCCCGGGTCATTGCGTGGGATGCACCCGGCTACGGC
GACTCCAGTGCACTGGAGTCGGACGTTCCCAAGGCTGAGCAGTACGCAGCACGTTTGGCACAGATGCTCGATGCATTGGA
GGTCGAAACCTTCGTGCTGGTGGGTCACTCACTGGGAGCCCTCACCGCCCTGGCGTTCGCCCGCAGTTCGCAGGCCCATC
GGGTGAGCCGCCTGGTGTTGATCAGCCCGGCTCGCGGTTATGGCGCACCGCAGCTGGCCCAACGGCGCCAACAGGTACGC
CAGCAGCGCCTGGACAACCTGCAACGTCTGGGTATCGCCGGCCTGGCCGAACAACGCAGCGCTCACATGTTGTCGCCGCG
TGCCACGCCCCAGGCCCTGGCCTGGGTGCGTTGGAACATGGCACGCCTGAACCCCGTCGGTTATCGCCAGGCGATTGAAT
TGCTGTGCGGCGATGACCTGCTGCGCCATGGCCAGCCGGCCATGCCCTGCGAGGTGCATTGCGGTGAAGCCGACAGCATC
ACCCCCGCCGAGGCCTGCCTGAGCGTGGCCAAGGCGCTGGGCGCCAGCTTCAACCTGATCGCCGACGCCGGCCACGCCAG
CCCCATCGAACAACCCCAAGTGGTTGCCGGGCGCCTGGCCTGTGCCCTCCAACAATCCCTGACAGGTACAACCCTATGA
Antitoxin
Download Length: 278 a.a. Molecular weight: 30601.10 Da Isoelectric Point: 6.9636
>AT27837 WP_003195671.1 NC_017911:5852955-5853788 [Pseudomonas fluorescens A506]
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD
MNDSDLLKDAQDKYIVPGLERGLLLLCEFSRRNRTLTAPELARRLALPRSTIFRLLTTLETMGFVTRSGNEYRLGMSVLR
LGFEYLASLELTELGQPLLARLCDRVNYPSNLVVRDGRSIVYVAKVSPPSVFSNAVNVGTRLPAHATVLGRILLEDLSLA
ELRELYPEEHLEQHSPCTPKTVMALFDLVQADRQRGFVSGEGFFESAISTVAAPVRDQSGGIVAALGVTIPTAQIGHVNF
EELLNQVRRSADELSRLLNYNGGAHNGQPRVTALMRD
Download Length: 834 bp
>AT27837 NC_017911:5852955-5853788 [Pseudomonas fluorescens A506]
ATGAACGATTCCGATCTGCTCAAAGACGCTCAGGACAAATACATCGTTCCCGGCCTTGAGCGCGGCCTGCTATTGCTCTG
TGAGTTCAGCCGGCGCAACCGCACCCTGACCGCACCGGAGCTGGCACGCCGCCTGGCACTGCCGCGCTCGACCATCTTCC
GCCTGCTGACCACCCTGGAGACCATGGGCTTCGTCACCCGCAGCGGTAATGAATATCGTCTCGGCATGTCCGTGCTGCGC
CTGGGTTTCGAGTACCTGGCGTCGCTGGAGCTGACCGAGCTTGGCCAGCCGCTGCTGGCGCGCTTGTGCGACCGGGTCAA
CTACCCGAGCAACCTGGTGGTGCGGGACGGTCGCTCGATTGTCTACGTGGCCAAGGTTTCACCGCCTTCGGTGTTCTCCA
ACGCGGTCAACGTCGGCACCCGCCTGCCCGCCCATGCCACCGTGCTGGGGCGCATCCTGCTCGAAGACCTGTCGCTGGCC
GAATTGCGTGAGTTGTACCCCGAAGAGCACCTGGAACAACACTCACCTTGCACGCCAAAAACCGTGATGGCGCTGTTCGA
CCTGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGTGGCGAAGGCTTTTTTGAATCGGCGATTTCCACGGTGGCCGCGC
CGGTGCGTGACCAGAGCGGCGGCATCGTCGCGGCTCTGGGCGTGACCATCCCCACGGCGCAGATCGGCCACGTCAATTTT
GAAGAACTCTTGAATCAGGTCCGGCGCAGCGCCGACGAGCTGTCACGCCTGCTCAACTACAACGGCGGCGCCCATAACGG
GCAGCCTCGCGTCACTGCCTTGATGAGAGACTGA
ATGAACGATTCCGATCTGCTCAAAGACGCTCAGGACAAATACATCGTTCCCGGCCTTGAGCGCGGCCTGCTATTGCTCTG
TGAGTTCAGCCGGCGCAACCGCACCCTGACCGCACCGGAGCTGGCACGCCGCCTGGCACTGCCGCGCTCGACCATCTTCC
GCCTGCTGACCACCCTGGAGACCATGGGCTTCGTCACCCGCAGCGGTAATGAATATCGTCTCGGCATGTCCGTGCTGCGC
CTGGGTTTCGAGTACCTGGCGTCGCTGGAGCTGACCGAGCTTGGCCAGCCGCTGCTGGCGCGCTTGTGCGACCGGGTCAA
CTACCCGAGCAACCTGGTGGTGCGGGACGGTCGCTCGATTGTCTACGTGGCCAAGGTTTCACCGCCTTCGGTGTTCTCCA
ACGCGGTCAACGTCGGCACCCGCCTGCCCGCCCATGCCACCGTGCTGGGGCGCATCCTGCTCGAAGACCTGTCGCTGGCC
GAATTGCGTGAGTTGTACCCCGAAGAGCACCTGGAACAACACTCACCTTGCACGCCAAAAACCGTGATGGCGCTGTTCGA
CCTGGTCCAGGCCGACCGCCAGCGCGGCTTTGTCAGTGGCGAAGGCTTTTTTGAATCGGCGATTTCCACGGTGGCCGCGC
CGGTGCGTGACCAGAGCGGCGGCATCGTCGCGGCTCTGGGCGTGACCATCCCCACGGCGCAGATCGGCCACGTCAATTTT
GAAGAACTCTTGAATCAGGTCCGGCGCAGCGCCGACGAGCTGTCACGCCTGCTCAACTACAACGGCGGCGCCCATAACGG
GCAGCCTCGCGTCACTGCCTTGATGAGAGACTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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