Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tad-ata/COG5606-COG4679
Location 296234..296835 Replicon plasmid unnamed2
Accession NZ_CP123002
Organism Neorhizobium petrolearium strain OS53

Toxin (Protein)


Gene name tad Uniprot ID -
Locus tag QEO92_RS32690 Protein ID WP_210058829.1
Coordinates 296234..296557 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name ata Uniprot ID -
Locus tag QEO92_RS32695 Protein ID WP_210058830.1
Coordinates 296554..296835 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEO92_RS32660 (QEO92_32660) 292192..292794 - 603 Protein_306 IS21 family transposase -
QEO92_RS32665 (QEO92_32665) 293121..294473 + 1353 WP_210058824.1 ISAs1 family transposase -
QEO92_RS32670 (QEO92_32670) 294556..294714 - 159 Protein_308 HU family DNA-binding protein -
QEO92_RS32675 (QEO92_32675) 294852..294980 - 129 Protein_309 WGR domain-containing protein -
QEO92_RS32680 (QEO92_32680) 295250..295498 + 249 WP_210058827.1 helix-turn-helix transcriptional regulator -
QEO92_RS32685 (QEO92_32685) 295528..295842 - 315 WP_210058828.1 hypothetical protein -
QEO92_RS32690 (QEO92_32690) 296234..296557 + 324 WP_210058829.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEO92_RS32695 (QEO92_32695) 296554..296835 + 282 WP_210058830.1 XRE family transcriptional regulator Antitoxin
QEO92_RS32700 (QEO92_32700) 296943..297437 - 495 WP_210058831.1 hypothetical protein -
QEO92_RS32705 (QEO92_32705) 297516..298172 - 657 WP_210058832.1 GNAT family N-acetyltransferase -
QEO92_RS32710 (QEO92_32710) 298332..298622 - 291 WP_210058833.1 DUF2285 domain-containing protein -
QEO92_RS32715 (QEO92_32715) 299216..301213 + 1998 WP_210058834.1 ParB/RepB/Spo0J family partition protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - htpB 1..379813 379813


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(13-101)

Antitoxin

HigA2-like, helix-turn-helix domain

(14-90)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 12243.01 Da        Isoelectric Point: 10.1375

>T278330 WP_210058829.1 NZ_CP123002:296234-296557 [Neorhizobium petrolearium]
MKAIEWLGSSRADVRSFPDDARVEAGWQLELVQRGDDPDDWKPMQAVGPGVREIRIREASGAFRVIYLATVEDRVLVLHA
FQKKTQAPSKKDLDLAAQRLKRWKAER

Download         Length: 324 bp

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10495.99 Da        Isoelectric Point: 6.4728

>AT278330 WP_210058830.1 NZ_CP123002:296554-296835 [Neorhizobium petrolearium]
MNVEIYENVWDALADTEQEAANLKARSALLYEIRKAVHRWDVPQEEAAKRLGLTRPRTNDLLRGKLAKFSLDALVNIAAS
AHLDIEIRVKEAA

Download         Length: 282 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References