Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | /RES-Xre |
| Location | 596276..597155 | Replicon | plasmid unnamed1 |
| Accession | NZ_CP123001 | ||
| Organism | Neorhizobium petrolearium strain OS53 | ||
Toxin (Protein)
| Gene name | - | Uniprot ID | A0A095VL40 |
| Locus tag | QEO92_RS29650 | Protein ID | WP_037145197.1 |
| Coordinates | 596640..597155 (+) | Length | 172 a.a. |
Antitoxin (Protein)
| Gene name | - | Uniprot ID | A0A095WTW0 |
| Locus tag | QEO92_RS29645 | Protein ID | WP_037145195.1 |
| Coordinates | 596276..596647 (+) | Length | 124 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QEO92_RS29625 (QEO92_29625) | 592535..593425 | - | 891 | WP_227705672.1 | AraC family transcriptional regulator | - |
| QEO92_RS29630 (QEO92_29630) | 593445..593771 | - | 327 | WP_227705673.1 | hypothetical protein | - |
| QEO92_RS29635 (QEO92_29635) | 594085..594468 | - | 384 | WP_227705674.1 | VOC family protein | - |
| QEO92_RS29640 (QEO92_29640) | 594564..596165 | - | 1602 | WP_227705675.1 | carboxypeptidase | - |
| QEO92_RS29645 (QEO92_29645) | 596276..596647 | + | 372 | WP_037145195.1 | DUF2384 domain-containing protein | Antitoxin |
| QEO92_RS29650 (QEO92_29650) | 596640..597155 | + | 516 | WP_037145197.1 | RES domain-containing protein | Toxin |
| QEO92_RS29655 (QEO92_29655) | 597380..597871 | - | 492 | WP_227705676.1 | MarR family transcriptional regulator | - |
| QEO92_RS29660 (QEO92_29660) | 597961..598752 | - | 792 | WP_227705677.1 | IclR family transcriptional regulator | - |
| QEO92_RS29665 (QEO92_29665) | 598848..599210 | + | 363 | WP_037145206.1 | Rieske 2Fe-2S domain-containing protein | - |
| QEO92_RS29670 (QEO92_29670) | 599197..599532 | + | 336 | WP_227705678.1 | hypothetical protein | - |
| QEO92_RS29675 (QEO92_29675) | 599572..600801 | + | 1230 | WP_037145212.1 | amidohydrolase family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..916660 | 916660 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 172 a.a. Molecular weight: 18799.20 Da Isoelectric Point: 5.9054
>T278328 WP_037145197.1 NZ_CP123001:596640-597155 [Neorhizobium petrolearium]
MPEPEEEALFLWRAYVPRWAHAPLSGDGAARFGGRWNPVGSPTIYAARELSTAWAEYNQGFVQHPALIAQLRLTGARLAN
LIDPAALADHGVNEAIHHCEWRADLDAGRLPATHALRERLVDQGFDGVVYPSFMSPGGTCVALWRWNGQGEPSLIVIDPD
GRLPRNAASWL
MPEPEEEALFLWRAYVPRWAHAPLSGDGAARFGGRWNPVGSPTIYAARELSTAWAEYNQGFVQHPALIAQLRLTGARLAN
LIDPAALADHGVNEAIHHCEWRADLDAGRLPATHALRERLVDQGFDGVVYPSFMSPGGTCVALWRWNGQGEPSLIVIDPD
GRLPRNAASWL
Download Length: 516 bp
Antitoxin
Download Length: 124 a.a. Molecular weight: 13106.09 Da Isoelectric Point: 9.5358
>AT278328 WP_037145195.1 NZ_CP123001:596276-596647 [Neorhizobium petrolearium]
MTAHAFEMSAASFSEAHSSFLSARRVSELLGVTQVELAKLIGVARNTLTAKSGARKVDLALSPVVRILAMASEMAGDENR
AAIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAVRSGVYA
MTAHAFEMSAASFSEAHSSFLSARRVSELLGVTQVELAKLIGVARNTLTAKSGARKVDLALSPVVRILAMASEMAGDENR
AAIWFKHQPIPGWAGKTAYDLVGEGKADKVLAYLEAVRSGVYA
Download Length: 372 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A095VL40 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A095WTW0 |