278327

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 416340..416875 Replicon plasmid unnamed1
Accession NZ_CP123001
Organism Neorhizobium petrolearium strain OS53

Toxin (Protein)


Gene name parE Uniprot ID A0A095WNQ3
Locus tag QEO92_RS28825 Protein ID WP_037148910.1
Coordinates 416585..416875 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A095VFW5
Locus tag QEO92_RS28820 Protein ID WP_037148912.1
Coordinates 416340..416588 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEO92_RS28805 (QEO92_28805) 411482..412186 - 705 WP_227705579.1 IS6 family transposase -
QEO92_RS28810 (QEO92_28810) 412307..415450 - 3144 WP_227705580.1 autotransporter outer membrane beta-barrel domain-containing protein -
QEO92_RS28815 (QEO92_28815) 415562..416137 + 576 Protein_392 IS5 family transposase -
QEO92_RS28820 (QEO92_28820) 416340..416588 + 249 WP_037148912.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
QEO92_RS28825 (QEO92_28825) 416585..416875 + 291 WP_037148910.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QEO92_RS28830 (QEO92_28830) 417439..419796 - 2358 WP_227705886.1 hypothetical protein -
QEO92_RS28835 (QEO92_28835) 420041..421222 + 1182 WP_227705581.1 Fic family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..916660 916660
- flank IS/Tn - - 411482..412186 704


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-91)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11083.59 Da        Isoelectric Point: 9.5945

>T278327 WP_037148910.1 NZ_CP123001:416585-416875 [Neorhizobium petrolearium]
MTGFILSPAAQADVERIWDYTATRWNVDQAERYIQNIRDACRALAAGTRVSRPVDIREGYRKVSVGSHFIYFKSNDTGQI
VVIRILHQRMDVDNRL

Download         Length: 291 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8851.87 Da        Isoelectric Point: 6.2180

>AT278327 WP_037148912.1 NZ_CP123001:416340-416588 [Neorhizobium petrolearium]
MARNTSISLGDHFATFIDTQVQAGRYGSASDVVRAGLRLLEEHEAKVKALHAALIEGEESGPATAFDFDAFNARKRAAFE
AK

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A095WNQ3

Antitoxin

Source ID Structure
AlphaFold DB A0A095VFW5

References