278326

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 306963..307753 Replicon plasmid unnamed1
Accession NZ_CP123001
Organism Neorhizobium petrolearium strain OS53

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QEO92_RS28365 Protein ID WP_227705509.1
Coordinates 307256..307753 (+) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag QEO92_RS28360 Protein ID WP_227705508.1
Coordinates 306963..307259 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEO92_RS28335 (QEO92_28335) 302898..303623 - 726 WP_227705503.1 SDR family oxidoreductase -
QEO92_RS28340 (QEO92_28340) 303878..304780 + 903 WP_227705504.1 LysR family transcriptional regulator -
QEO92_RS28345 (QEO92_28345) 305185..305628 - 444 WP_227705505.1 hypothetical protein -
QEO92_RS28350 (QEO92_28350) 305732..306487 - 756 WP_227705506.1 hypothetical protein -
QEO92_RS28355 (QEO92_28355) 306462..306683 + 222 WP_227705507.1 hypothetical protein -
QEO92_RS28360 (QEO92_28360) 306963..307259 + 297 WP_227705508.1 DUF1778 domain-containing protein Antitoxin
QEO92_RS28365 (QEO92_28365) 307256..307753 + 498 WP_227705509.1 GNAT family N-acetyltransferase Toxin
QEO92_RS28370 (QEO92_28370) 307904..308950 - 1047 WP_227705510.1 LacI family DNA-binding transcriptional regulator -
QEO92_RS28375 (QEO92_28375) 309100..310047 + 948 WP_227705511.1 dihydrodipicolinate synthase family protein -
QEO92_RS28380 (QEO92_28380) 310303..311487 + 1185 WP_280107549.1 Nramp family divalent metal transporter -
QEO92_RS28385 (QEO92_28385) 311776..312672 - 897 WP_227705513.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..916660 916660


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(43-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17806.31 Da        Isoelectric Point: 6.8723

>T278326 WP_227705509.1 NZ_CP123001:307256-307753 [Neorhizobium petrolearium]
VTLSAPAPLAEHHELAEFNSGVAELDDWLRRRARSNQASGASRTFVVCDESRVIAYYALASGAVKQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSYQGRGIGRALVRDAGLRLLNAAEVLGIRGMLVHAISDDARAFYEAVGFLSSPSDPMMLMVGLHDLN
NALNP

Download         Length: 498 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11063.55 Da        Isoelectric Point: 5.8769

>AT278326 WP_227705508.1 NZ_CP123001:306963-307259 [Neorhizobium petrolearium]
MPTSHTSKSSDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRTIFTVGPEIYAEYLARLDAPTQ
PNERLTRTMSTKAPWDEA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References