278322

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2826722..2827512 Replicon chromosome
Accession NZ_CP123000
Organism Neorhizobium petrolearium strain OS53

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag QEO92_RS14100 Protein ID WP_227703476.1
Coordinates 2826722..2827219 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID A0A095VJJ4
Locus tag QEO92_RS14105 Protein ID WP_037146495.1
Coordinates 2827216..2827512 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEO92_RS14090 (QEO92_14090) 2823322..2823978 + 657 WP_052182652.1 TetR/AcrR family transcriptional regulator -
QEO92_RS14095 (QEO92_14095) 2824474..2826366 + 1893 WP_227703475.1 PhoX family phosphatase -
QEO92_RS14100 (QEO92_14100) 2826722..2827219 - 498 WP_227703476.1 GNAT family N-acetyltransferase Toxin
QEO92_RS14105 (QEO92_14105) 2827216..2827512 - 297 WP_037146495.1 DUF1778 domain-containing protein Antitoxin
QEO92_RS14110 (QEO92_14110) 2828125..2829663 - 1539 WP_037146497.1 Fic family protein -
QEO92_RS14115 (QEO92_14115) 2829675..2829935 + 261 WP_152601039.1 hypothetical protein -
QEO92_RS14120 (QEO92_14120) 2830051..2831025 - 975 WP_037146498.1 AraC family transcriptional regulator -
QEO92_RS14125 (QEO92_14125) 2831196..2831555 + 360 WP_037146500.1 c-type cytochrome -
QEO92_RS14130 (QEO92_14130) 2831573..2832025 + 453 WP_037146502.1 (2Fe-2S)-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(45-142)

Antitoxin

Vibrio phage ICP1, Orf50

(16-90)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 17609.10 Da        Isoelectric Point: 6.8718

>T278322 WP_227703476.1 NZ_CP123000:c2827219-2826722 [Neorhizobium petrolearium]
VTLSAPAPLADHHELADFNSGVPELDDWLRRRARANQAGGASRTFVVCEGIGVIAYYALASGAVKQPEAPGRFRRNMPDP
IPVAVLGRLAIDQSYQGRGIGRALVRDAGLRLRNAAEVLGIRGVLVHAISDDARAFYEAVGFLPSPSDPMMLMVGLHDLN
DALNG

Download         Length: 498 bp

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11096.80 Da        Isoelectric Point: 8.6351

>AT278322 WP_037146495.1 NZ_CP123000:c2827512-2827216 [Neorhizobium petrolearium]
MPTSRPSKSPDASVPLNMRIKPATRNLIDRAAELLGKTRTDFMLEASERRAEEVLLDRIIFTVSPEIFAEYLARLDAPAP
LNERLKRTMSTKAPWDEA

Download         Length: 297 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A095VJJ4

References