278317

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PemK-MazE
Location 504852..505390 Replicon chromosome
Accession NZ_CP123000
Organism Neorhizobium petrolearium strain OS53

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag QEO92_RS02580 Protein ID WP_227702056.1
Coordinates 505067..505390 (+) Length 108 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag QEO92_RS02575 Protein ID WP_081953014.1
Coordinates 504852..505067 (+) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QEO92_RS02550 (QEO92_02550) 500072..500689 - 618 WP_227702052.1 hypothetical protein -
QEO92_RS02555 (QEO92_02555) 501162..502409 + 1248 WP_227702053.1 aromatic ring-hydroxylating dioxygenase subunit alpha -
QEO92_RS02560 (QEO92_02560) 502529..502960 + 432 WP_227702054.1 BA14K family protein -
QEO92_RS02565 (QEO92_02565) 503152..503643 + 492 WP_227702055.1 BA14K family protein -
QEO92_RS02570 (QEO92_02570) 503713..504708 - 996 WP_037159853.1 transporter -
QEO92_RS02575 (QEO92_02575) 504852..505067 + 216 WP_081953014.1 antitoxin MazE family protein Antitoxin
QEO92_RS02580 (QEO92_02580) 505067..505390 + 324 WP_227702056.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
QEO92_RS02585 (QEO92_02585) 505476..507281 + 1806 WP_227702057.1 acyl-CoA dehydrogenase -
QEO92_RS02590 (QEO92_02590) 507347..508054 + 708 WP_280107517.1 crotonase/enoyl-CoA hydratase family protein -
QEO92_RS02595 (QEO92_02595) 508140..508442 + 303 WP_227702059.1 hypothetical protein -
QEO92_RS02600 (QEO92_02600) 508443..509687 - 1245 WP_227702060.1 class I SAM-dependent RNA methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(2-104)

Antitoxin

Antitoxin MazE-like

(7-68)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11711.62 Da        Isoelectric Point: 6.2790

>T278317 WP_227702056.1 NZ_CP123000:505067-505390 [Neorhizobium petrolearium]
MQRGDLVTVALTGDFGKPRPALIVQSDLFDETDTLTVLLLSSTLVNAPLVRLTVQPDATNALNKPSQIMVDKTMTVRRDK
LGKVFGRIDDETMISVTRSLAVFFGFA

Download         Length: 324 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 7929.98 Da        Isoelectric Point: 6.2922

>AT278317 WP_081953014.1 NZ_CP123000:504852-505067 [Neorhizobium petrolearium]
MPSSVSERVRKRRESLRAAGLRPLQIWVPDTRRPGFAEECRRQSRVVAAADAADPDLLNFLDEALADLGEP

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References