278307

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/upstrm_HI1419-dnstrm_HI1420
Location 3363507..3364126 Replicon chromosome
Accession NZ_CP122987
Organism Aeromonas salmonicida strain JNG

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag QDU35_RS15885 Protein ID WP_085044624.1
Coordinates 3363507..3363803 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QDU35_RS15890 Protein ID WP_085044625.1
Coordinates 3363806..3364126 (+) Length 107 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDU35_RS15860 (QDU35_15860) 3358807..3359043 + 237 WP_139804925.1 hypothetical protein -
QDU35_RS15865 (QDU35_15865) 3359040..3359921 + 882 WP_085044620.1 hypothetical protein -
QDU35_RS15870 (QDU35_15870) 3359918..3360466 + 549 WP_085044621.1 hypothetical protein -
QDU35_RS15875 (QDU35_15875) 3360463..3362076 + 1614 WP_085044622.1 hypothetical protein -
QDU35_RS15880 (QDU35_15880) 3362088..3362786 + 699 WP_085044623.1 phage virion morphogenesis protein -
QDU35_RS15885 (QDU35_15885) 3363507..3363803 + 297 WP_085044624.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
QDU35_RS15890 (QDU35_15890) 3363806..3364126 + 321 WP_085044625.1 putative addiction module antidote protein Antitoxin
QDU35_RS15895 (QDU35_15895) 3364345..3365712 + 1368 WP_085044626.1 hypothetical protein -
QDU35_RS15900 (QDU35_15900) 3366433..3367344 + 912 WP_042468381.1 LysR family transcriptional regulator -
QDU35_RS15905 (QDU35_15905) 3367561..3367911 + 351 WP_005312972.1 ArsC family reductase -
QDU35_RS15910 (QDU35_15910) 3367931..3369058 + 1128 WP_005312969.1 succinyl-diaminopimelate desuccinylase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3333427..3365712 32285


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(50-94)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11025.77 Da        Isoelectric Point: 10.1760

>T278307 WP_085044624.1 NZ_CP122987:3363507-3363803 [Aeromonas salmonicida]
MREIIKTNVFDRWFDSLRDARAQAKVTARIRRLGLGNPGDVKPIGEGLSEMRIDYGPGYRVYFMTKGPIIIVLLCGGDKG
TQARDIEQAKTIAAQWKD

Download         Length: 297 bp

Antitoxin


Download         Length: 107 a.a.        Molecular weight: 11417.87 Da        Isoelectric Point: 5.0944

>AT278307 WP_085044625.1 NZ_CP122987:3363806-3364126 [Aeromonas salmonicida]
MKDHEQTVTFSRYDAADYLKTDEDMLHYLEAVMEEGDPALIAAALGDIARARNLSQLARDVGMSREGLYKALSGEGNPTF
ATITKVAGALGLRFGVHLANPPATHA

Download         Length: 321 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References