Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 318536..319016 Replicon chromosome
Accession NZ_CP122962
Organism Agrobacterium tumefaciens strain CFBP5506

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag CFBP5506_RS01525 Protein ID WP_080791291.1
Coordinates 318536..318805 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CFBP5506_RS01530 Protein ID WP_080791290.1
Coordinates 318789..319016 (-) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CFBP5506_RS01495 (CFBP5506_01495) 313599..314375 - 777 WP_080791296.1 L,D-transpeptidase -
CFBP5506_RS01500 (CFBP5506_01500) 314611..315240 + 630 WP_080791295.1 DNA-3-methyladenine glycosylase I -
CFBP5506_RS01505 (CFBP5506_01505) 315237..315680 + 444 WP_080791294.1 hypothetical protein -
CFBP5506_RS01510 (CFBP5506_01510) 315696..316739 - 1044 WP_121459701.1 YeiH family protein -
CFBP5506_RS01515 (CFBP5506_01515) 316822..317739 + 918 WP_080791293.1 LysR family transcriptional regulator -
CFBP5506_RS01520 (CFBP5506_01520) 317765..318529 - 765 WP_080791292.1 hypothetical protein -
CFBP5506_RS01525 (CFBP5506_01525) 318536..318805 - 270 WP_080791291.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CFBP5506_RS01530 (CFBP5506_01530) 318789..319016 - 228 WP_080791290.1 DUF6290 family protein Antitoxin
CFBP5506_RS01535 (CFBP5506_01535) 319251..320774 + 1524 WP_080791289.1 histidine--tRNA ligase -
CFBP5506_RS01540 (CFBP5506_01540) 320779..321147 + 369 WP_080791288.1 VOC family protein -
CFBP5506_RS01545 (CFBP5506_01545) 321164..322291 + 1128 WP_080791287.1 ATP phosphoribosyltransferase regulatory subunit -
CFBP5506_RS01550 (CFBP5506_01550) 322288..322980 + 693 WP_080791286.1 ATP phosphoribosyltransferase -
CFBP5506_RS01555 (CFBP5506_01555) 323040..323486 - 447 WP_080791285.1 DoxX family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-88)

Antitoxin

Protein of unknown function DUF6290

(6-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10774.42 Da        Isoelectric Point: 9.5684

>T278303 WP_080791291.1 NZ_CP122962:c318805-318536 [Agrobacterium tumefaciens]
VIWTIEYDTLVQKEMRKIHPEVRRRIRSFLHERIAALDDPRQTGTTLQGSELGNFWRYRVGDYRIICDIQDHKLVVLVVE
IGHRREIYR

Download         Length: 270 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8954.03 Da        Isoelectric Point: 4.7254

>AT278303 WP_080791290.1 NZ_CP122962:c319016-318789 [Agrobacterium tumefaciens]
MSKQTAIRLPDETYERLKALSERTGRTSAYYIREAIEKHIEDMEDLYLAEEAMRRIQRGESKVISAEEFWRDLDN

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References