278299

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 587752..588408 Replicon chromosome
Accession NZ_CP122956
Organism Helicobacter pylori strain BT112

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QAD58_RS02855 Protein ID WP_286448704.1
Coordinates 587752..588018 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QAD58_RS02860 Protein ID WP_120923865.1
Coordinates 588097..588408 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAD58_RS02830 (QAD58_02835) 583471..583992 - 522 WP_286448702.1 hypothetical protein -
QAD58_RS02845 (QAD58_02850) 584498..586714 + 2217 WP_286448703.1 Hop family adhesin BabA -
QAD58_RS02850 (QAD58_02855) 587394..587771 + 378 WP_001133862.1 hypothetical protein -
QAD58_RS02855 (QAD58_02860) 587752..588018 + 267 WP_286448704.1 type II toxin-antitoxin system YafQ family toxin Toxin
QAD58_RS02860 (QAD58_02865) 588097..588408 + 312 WP_120923865.1 type II toxin-antitoxin system antitoxin Antitoxin
QAD58_RS02865 (QAD58_02870) 588395..588532 + 138 Protein_544 type II toxin-antitoxin system YafQ family toxin -
QAD58_RS02870 (QAD58_02875) 588586..589107 - 522 WP_286446122.1 acyl-CoA thioesterase -
QAD58_RS02875 (QAD58_02880) 589247..590089 + 843 WP_286448706.1 SDR family oxidoreductase -
QAD58_RS02880 (QAD58_02885) 590082..591062 + 981 WP_000921452.1 iron ABC transporter permease -
QAD58_RS02885 (QAD58_02890) 591062..591829 + 768 WP_220884645.1 ABC transporter ATP-binding protein -
QAD58_RS02890 (QAD58_02895) 591906..593018 + 1113 WP_286448993.1 glycosyltransferase family 8 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10318.14 Da        Isoelectric Point: 8.0602

>T278299 WP_286448704.1 NZ_CP122956:587752-588018 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILTLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELVLLR
LGSHSELF

Download         Length: 267 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12279.04 Da        Isoelectric Point: 9.9013

>AT278299 WP_120923865.1 NZ_CP122956:588097-588408 [Helicobacter pylori]
MPNTTAEKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKSVEDFKKHCENLRFKNADD

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References