Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1094982..1095600 Replicon chromosome
Accession NZ_CP122955
Organism Helicobacter pylori strain BS27-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QAP03_RS05185 Protein ID WP_286492538.1
Coordinates 1094982..1095242 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QAP03_RS05190 Protein ID WP_286492525.1
Coordinates 1095229..1095600 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAP03_RS05165 (QAP03_05160) 1091618..1092385 - 768 WP_000242357.1 ABC transporter ATP-binding protein -
QAP03_RS05170 (QAP03_05165) 1092385..1093365 - 981 WP_000921458.1 iron chelate uptake ABC transporter family permease subunit -
QAP03_RS05175 (QAP03_05170) 1093358..1094212 - 855 WP_286492554.1 SDR family oxidoreductase -
QAP03_RS05180 (QAP03_05175) 1094352..1094876 + 525 WP_001135623.1 acyl-CoA thioesterase -
QAP03_RS05185 (QAP03_05180) 1094982..1095242 - 261 WP_286492538.1 type II toxin-antitoxin system YafQ family toxin Toxin
QAP03_RS05190 (QAP03_05185) 1095229..1095600 - 372 WP_286492525.1 hypothetical protein Antitoxin
QAP03_RS05195 (QAP03_05190) 1095936..1098066 - 2131 Protein_1020 Hop family adhesin BabB -
QAP03_RS05210 (QAP03_05205) 1098458..1099111 + 654 Protein_1021 helicase DnaB modulator -
QAP03_RS05215 (QAP03_05210) 1099062..1100174 - 1113 WP_286492515.1 hydrogenase formation protein HypD -
QAP03_RS05220 (QAP03_05215) 1100193..1100429 - 237 WP_000335476.1 HypC/HybG/HupF family hydrogenase formation chaperone -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10284.15 Da        Isoelectric Point: 9.9833

>T278297 WP_286492538.1 NZ_CP122955:c1095242-1094982 [Helicobacter pylori]
MLKIRHHIFFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPQFQDHALKGKWKPFRECHIKADVLLVYLVRDDELVLLRLG
SHSELF

Download         Length: 261 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14404.29 Da        Isoelectric Point: 6.4061

>AT278297 WP_286492525.1 NZ_CP122955:c1095600-1095229 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNGLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALNGENLETIEDFSAWANEVKKEMNAEN

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References