Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 557117..557735 Replicon chromosome
Accession NZ_CP122952
Organism Helicobacter pylori strain BS27-1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QAP05_RS02740 Protein ID WP_286492538.1
Coordinates 557475..557735 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QAP05_RS02735 Protein ID WP_286492525.1
Coordinates 557117..557488 (+) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAP05_RS02705 (QAP05_02705) 552288..552524 + 237 WP_000335476.1 HypC/HybG/HupF family hydrogenase formation chaperone -
QAP05_RS02710 (QAP05_02710) 552543..553655 + 1113 WP_286492515.1 hydrogenase formation protein HypD -
QAP05_RS02715 (QAP05_02715) 553606..554259 - 654 Protein_517 helicase DnaB modulator -
QAP05_RS02730 (QAP05_02730) 554651..556781 + 2131 Protein_518 Hop family adhesin BabB -
QAP05_RS02735 (QAP05_02735) 557117..557488 + 372 WP_286492525.1 hypothetical protein Antitoxin
QAP05_RS02740 (QAP05_02740) 557475..557735 + 261 WP_286492538.1 type II toxin-antitoxin system YafQ family toxin Toxin
QAP05_RS02745 (QAP05_02745) 557841..558365 - 525 WP_001135623.1 acyl-CoA thioesterase -
QAP05_RS02750 (QAP05_02750) 558505..559359 + 855 WP_286492554.1 SDR family oxidoreductase -
QAP05_RS02755 (QAP05_02755) 559352..560332 + 981 WP_000921458.1 iron chelate uptake ABC transporter family permease subunit -
QAP05_RS02760 (QAP05_02760) 560332..561099 + 768 WP_000242357.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(3-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10284.15 Da        Isoelectric Point: 9.9833

>T278294 WP_286492538.1 NZ_CP122952:557475-557735 [Helicobacter pylori]
MLKIRHHIFFKKDFKKLVKNGFDDSVLNEVILRKKEPLDPQFQDHALKGKWKPFRECHIKADVLLVYLVRDDELVLLRLG
SHSELF

Download         Length: 261 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 14404.29 Da        Isoelectric Point: 6.4061

>AT278294 WP_286492525.1 NZ_CP122952:557117-557488 [Helicobacter pylori]
MPNSPTKKDYTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNGLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALNGENLETIEDFSAWANEVKKEMNAEN

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References