278289

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 606594..607146 Replicon chromosome
Accession NZ_CP122948
Organism Helicobacter pylori strain BS21

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QAP02_RS02945 Protein ID WP_286464661.1
Coordinates 606889..607146 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QAP02_RS02940 Protein ID WP_286464660.1
Coordinates 606594..606902 (+) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAP02_RS02920 (QAP02_02920) 602643..603280 - 638 Protein_557 helicase DnaB modulator -
QAP02_RS02935 (QAP02_02935) 603682..605910 + 2229 WP_286464659.1 Hop family adhesin BabA -
QAP02_RS02940 (QAP02_02940) 606594..606902 + 309 WP_286464660.1 type II toxin-antitoxin system antitoxin Antitoxin
QAP02_RS02945 (QAP02_02945) 606889..607146 + 258 WP_286464661.1 YafQ family addiction module toxin Toxin
QAP02_RS02950 (QAP02_02950) 607208..608356 - 1149 WP_286462925.1 transposase -
QAP02_RS02955 (QAP02_02955) 608325..608792 - 468 WP_000063685.1 IS200/IS605 family transposase -
QAP02_RS02960 (QAP02_02960) 609094..609618 - 525 WP_001135623.1 acyl-CoA thioesterase -
QAP02_RS02965 (QAP02_02965) 609758..610612 + 855 WP_286464662.1 SDR family oxidoreductase -
QAP02_RS02970 (QAP02_02970) 610605..611585 + 981 WP_000921461.1 iron ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-80)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9908.86 Da        Isoelectric Point: 10.0317

>T278289 WP_286464661.1 NZ_CP122948:606889-607146 [Helicobacter pylori]
MLMIETSKKFDKDLKILVKNGFDLKLLYKVVGNLAKEQPLASKYKDHPLKGALKDFRECHLKPDLLLVYQIKKQENTLFL
LTYSP

Download         Length: 258 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 12261.08 Da        Isoelectric Point: 10.3079

>AT278289 WP_286464660.1 NZ_CP122948:606594-606902 [Helicobacter pylori]
MPNTTNKDYTKYSQRQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNHL
CFKNIEDFKKHCENLRFKNADD

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References