Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 1059494..1060685 Replicon chromosome
Accession NZ_CP122947
Organism Helicobacter pylori strain BS07

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag QAD57_RS04980 Protein ID WP_286445386.1
Coordinates 1059494..1060258 (-) Length 255 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag QAD57_RS04985 Protein ID WP_096521412.1
Coordinates 1060248..1060685 (-) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAD57_RS04970 (QAD57_04965) 1056826..1057986 + 1161 WP_286445384.1 aminotransferase class V-fold PLP-dependent enzyme -
QAD57_RS04975 (QAD57_04970) 1058074..1059261 + 1188 WP_286445385.1 transcription termination factor NusA -
QAD57_RS04980 (QAD57_04975) 1059494..1060258 - 765 WP_286445386.1 hypothetical protein Toxin
QAD57_RS04985 (QAD57_04980) 1060248..1060685 - 438 WP_096521412.1 Panacea domain-containing protein Antitoxin
QAD57_RS04990 (QAD57_04985) 1060911..1062317 - 1407 WP_286445387.1 RNA-directed DNA polymerase -
QAD57_RS04995 (QAD57_04990) 1062566..1063087 - 522 WP_286445388.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(24-119)


Sequences

Toxin        


Download         Length: 255 a.a.        Molecular weight: 29763.67 Da        Isoelectric Point: 8.3838

>T278288 WP_286445386.1 NZ_CP122947:c1060258-1059494 [Helicobacter pylori]
METKEEDKDKKLEEIIVSLCKEGDLSGQKDQIIKDLKEIYEGEYRHKYSKITTIILNSTRDKEQAFMTLTQNIRTLKEIQ
DNKEVESIKPKLEKLYDHINLECIRLQDFDEKMSRVKDVSIRLEDDLNKNYKKLSEELNKQQTQYITILGIFASIVLTFV
GGLAFSTSVLSNIDKANAYRLVFVMAFIALFFGNILYLLFSFLSKISLSKEKKDKQENFFKKSIFWFNLMVTILFVIGFV
GELHIIQRLASKYF

Download         Length: 765 bp

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 17281.41 Da        Isoelectric Point: 6.2653

>AT278288 WP_096521412.1 NZ_CP122947:c1060685-1060248 [Helicobacter pylori]
MVNALELAKYILKRSNKELSNLELQKTLYFTELDYIKKFDKHLVSDDFEAWKYGPVAREVYYEYRNYGANSIDKPKEETL
SQNLRKDELETINYSIEKCNEKSYWDLVKESHKEDGAWHKSFKEDRKEVISKDLIKQEAKQANGN

Download         Length: 438 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References