278284

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1078165..1078789 Replicon chromosome
Accession NZ_CP122946
Organism Helicobacter pylori strain BS31

Toxin (Protein)


Gene name relE Uniprot ID A0A2A6UH71
Locus tag QAP07_RS05105 Protein ID WP_025455067.1
Coordinates 1078165..1078431 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QAP07_RS05110 Protein ID WP_286443894.1
Coordinates 1078412..1078789 (-) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QAP07_RS05085 (QAP07_05085) 1074807..1075574 - 768 WP_000242349.1 ABC transporter ATP-binding protein -
QAP07_RS05090 (QAP07_05090) 1075574..1076554 - 981 WP_000921461.1 iron ABC transporter permease -
QAP07_RS05095 (QAP07_05095) 1076547..1077395 - 849 WP_286443886.1 SDR family oxidoreductase -
QAP07_RS05100 (QAP07_05100) 1077536..1078060 + 525 WP_121297461.1 acyl-CoA thioesterase -
QAP07_RS05105 (QAP07_05105) 1078165..1078431 - 267 WP_025455067.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
QAP07_RS05110 (QAP07_05110) 1078412..1078789 - 378 WP_286443894.1 hypothetical protein Antitoxin
QAP07_RS05115 (QAP07_05115) 1078870..1079136 - 267 WP_101003364.1 type II toxin-antitoxin system YafQ family toxin -
QAP07_RS05120 (QAP07_05120) 1079123..1079494 - 372 WP_286443900.1 hypothetical protein -
QAP07_RS05125 (QAP07_05125) 1080143..1082365 - 2223 WP_286443903.1 Hop family adhesin BabA -
QAP07_RS05140 (QAP07_05140) 1082885..1083406 + 522 WP_286443905.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-88)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10303.17 Da        Isoelectric Point: 9.6292

>T278284 WP_025455067.1 NZ_CP122946:c1078431-1078165 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNKVILSLRKKEPLDPQFQDHALKGKWKPFRECHIKADILLVYLVKDDELILVR
LGSHSELF

Download         Length: 267 bp

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14622.58 Da        Isoelectric Point: 8.4602

>AT278284 WP_286443894.1 NZ_CP122946:c1078789-1078412 [Helicobacter pylori]
MPNTTAKKDYTQYSEKQLFNLINQLEQKIKKMQNDRASFKEKMAKELDKRDQNFKDKIDALNGLLQKISQAFDDKRDCCL
GRKIPNLETQQAMRDALNKETDLIVEDFSSYSDERKRALGVETQP

Download         Length: 378 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2A6UH71

Antitoxin

Source ID Structure

References