Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2068727..2068961 Replicon chromosome
Accession NZ_CP122923
Organism Escherichia coli strain ETEC1703

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2068857..2068960 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2068727..2068961 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX14_RS09995 2065283..2065945 - 663 WP_000944258.1 exodeoxyribonuclease X -
QDX14_RS10000 2065968..2066624 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QDX14_RS10005 2066726..2066956 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDX14_RS10010 2067095..2067469 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QDX14_RS10015 2067473..2068345 + 873 WP_000879295.1 copper homeostasis membrane protein CopD -
QDX14_RS10020 2068358..2068699 + 342 WP_000976472.1 YebY family protein -
- 2068727..2068961 - 235 - - Antitoxin
- 2068857..2068960 + 104 - - Toxin
QDX14_RS10025 2069092..2070168 - 1077 WP_053508942.1 phage integrase Arm DNA-binding domain-containing protein -
QDX14_RS10030 2070134..2070415 - 282 WP_077248935.1 excisionase -
QDX14_RS10035 2070522..2070710 - 189 WP_021529595.1 DUF1187 family protein -
- 2070526..2070704 + 179 NuclAT_1 - -
- 2070526..2070704 + 179 NuclAT_1 - -
- 2070526..2070704 + 179 NuclAT_1 - -
- 2070526..2070704 + 179 NuclAT_1 - -
QDX14_RS10040 2070703..2070897 - 195 WP_187182214.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
QDX14_RS10045 2070961..2072049 - 1089 WP_230905604.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2063226..2134919 71693


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T278208 NZ_CP122923:2068857-2068960 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT278208 NZ_CP122923:c2068961-2068727 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References