Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1132281..1133116 Replicon chromosome
Accession NZ_CP122876
Organism Escherichia coli strain ETEC1717

Toxin (Protein)


Gene name yeeV Uniprot ID A0A8S7S8K0
Locus tag QDX11_RS05490 Protein ID WP_000854723.1
Coordinates 1132281..1132658 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A8S7S6L8
Locus tag QDX11_RS05495 Protein ID WP_001285573.1
Coordinates 1132748..1133116 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX11_RS05465 (1127659) 1127659..1129911 - 2253 Protein_1069 alpha-amylase family glycosyl hydrolase -
QDX11_RS05475 (1130645) 1130645..1131490 - 846 WP_001290254.1 DUF4942 domain-containing protein -
QDX11_RS05480 (1131587) 1131587..1131784 - 198 WP_000772035.1 DUF957 domain-containing protein -
QDX11_RS05485 (1131796) 1131796..1132284 - 489 WP_000761669.1 DUF5983 family protein -
QDX11_RS05490 (1132281) 1132281..1132658 - 378 WP_000854723.1 TA system toxin CbtA family protein Toxin
QDX11_RS05495 (1132748) 1132748..1133116 - 369 WP_001285573.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QDX11_RS05500 (1133196) 1133196..1133417 - 222 WP_000692176.1 DUF987 domain-containing protein -
QDX11_RS05505 (1133504) 1133504..1133980 - 477 WP_001360063.1 RadC family protein -
QDX11_RS05510 (1133996) 1133996..1134490 - 495 WP_032167345.1 antirestriction protein -
QDX11_RS05515 (1134582) 1134582..1135400 - 819 WP_032167344.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1128874..1153876 25002


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14145.23 Da        Isoelectric Point: 8.2904

>T278159 WP_000854723.1 NZ_CP122876:c1132658-1132281 [Escherichia coli]
MKTLPDTHVREASRCPSPVTIWQILLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
STCTRSQLINSIDILRTRRATGLMARDNYRTVNNIILGKHPGAKQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13585.33 Da        Isoelectric Point: 6.3159

>AT278159 WP_001285573.1 NZ_CP122876:c1133116-1132748 [Escherichia coli]
VSDTLPGTTHPDDNNDRPWWGLPCSVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADSYHLDQAFPLLMKQLELMLTSG
ELSPRHQHTVTLYAKGLTCEADTLGSCGYVYMAVYPTPETKK

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References