Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yeeUV (cbtA-cbeA)/CbtA-CbeA
Location 1132280..1133115 Replicon chromosome
Accession NZ_CP122872
Organism Escherichia coli strain ETEC1718

Toxin (Protein)


Gene name yeeV Uniprot ID A0A8S7S8K0
Locus tag QDX06_RS05485 Protein ID WP_000854723.1
Coordinates 1132280..1132657 (-) Length 126 a.a.

Antitoxin (Protein)


Gene name yeeU Uniprot ID A0A8S7S6L8
Locus tag QDX06_RS05490 Protein ID WP_001285573.1
Coordinates 1132747..1133115 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX06_RS05460 (1127658) 1127658..1129910 - 2253 Protein_1068 alpha-amylase family glycosyl hydrolase -
QDX06_RS05470 (1130644) 1130644..1131489 - 846 WP_001290254.1 DUF4942 domain-containing protein -
QDX06_RS05475 (1131586) 1131586..1131783 - 198 WP_000772035.1 DUF957 domain-containing protein -
QDX06_RS05480 (1131795) 1131795..1132283 - 489 WP_000761669.1 DUF5983 family protein -
QDX06_RS05485 (1132280) 1132280..1132657 - 378 WP_000854723.1 TA system toxin CbtA family protein Toxin
QDX06_RS05490 (1132747) 1132747..1133115 - 369 WP_001285573.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
QDX06_RS05495 (1133195) 1133195..1133416 - 222 WP_000692176.1 DUF987 domain-containing protein -
QDX06_RS05500 (1133503) 1133503..1133979 - 477 WP_001360063.1 RadC family protein -
QDX06_RS05505 (1133995) 1133995..1134489 - 495 WP_032167345.1 antirestriction protein -
QDX06_RS05510 (1134581) 1134581..1135399 - 819 WP_032167344.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1128873..1153875 25002


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(18-117)


Sequences

Toxin        


Download         Length: 126 a.a.        Molecular weight: 14145.23 Da        Isoelectric Point: 8.2904

>T278139 WP_000854723.1 NZ_CP122872:c1132657-1132280 [Escherichia coli]
MKTLPDTHVREASRCPSPVTIWQILLTRLLDQHYGLTLNDTPFADERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGF
STCTRSQLINSIDILRTRRATGLMARDNYRTVNNIILGKHPGAKQ

Download         Length: 378 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 13585.33 Da        Isoelectric Point: 6.3159

>AT278139 WP_001285573.1 NZ_CP122872:c1133115-1132747 [Escherichia coli]
VSDTLPGTTHPDDNNDRPWWGLPCSVTPCFGARLVQEGNRLHYLADRAGIRGRFSDADSYHLDQAFPLLMKQLELMLTSG
ELSPRHQHTVTLYAKGLTCEADTLGSCGYVYMAVYPTPETKK

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References