Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | parDE/RelE-RHH |
Location | 12755..13302 | Replicon | plasmid unnamed3 |
Accession | NZ_CP122871 | ||
Organism | Escherichia coli strain ETEC1721 |
Toxin (Protein)
Gene name | parE | Uniprot ID | G7QEJ9 |
Locus tag | QDX04_RS23610 | Protein ID | WP_001384452.1 |
Coordinates | 13024..13302 (+) | Length | 93 a.a. |
Antitoxin (Protein)
Gene name | parD | Uniprot ID | A0A2I6FMZ7 |
Locus tag | QDX04_RS23605 | Protein ID | WP_000079930.1 |
Coordinates | 12755..13024 (+) | Length | 90 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QDX04_RS23575 (7866) | 7866..8177 | - | 312 | WP_000765906.1 | hypothetical protein | - |
- (8473) | 8473..8534 | - | 62 | NuclAT_1 | - | - |
- (8473) | 8473..8534 | - | 62 | NuclAT_1 | - | - |
- (8473) | 8473..8534 | - | 62 | NuclAT_1 | - | - |
- (8473) | 8473..8534 | - | 62 | NuclAT_1 | - | - |
QDX04_RS23585 (9839) | 9839..9979 | + | 141 | WP_064717426.1 | Hok/Gef family protein | - |
QDX04_RS23590 (10259) | 10259..10516 | + | 258 | WP_000083834.1 | replication regulatory protein RepA | - |
QDX04_RS23595 (10750) | 10750..10824 | + | 75 | WP_032319616.1 | RepA leader peptide Tap | - |
QDX04_RS23600 (10817) | 10817..11839 | + | 1023 | WP_000840938.1 | plasmid replication initiator RepA | - |
QDX04_RS23605 (12755) | 12755..13024 | + | 270 | WP_000079930.1 | type II toxin-antitoxin system antitoxin YacA | Antitoxin |
QDX04_RS23610 (13024) | 13024..13302 | + | 279 | WP_001384452.1 | type II toxin-antitoxin system toxin YacB | Toxin |
QDX04_RS23615 (13348) | 13348..14077 | + | 730 | Protein_15 | 3'-5' exonuclease | - |
QDX04_RS23620 (14084) | 14084..14392 | - | 309 | Protein_16 | integrase core domain-containing protein | - |
QDX04_RS23625 (14409) | 14409..15485 | - | 1077 | WP_039022834.1 | IS110-like element ISEc21 family transposase | - |
QDX04_RS23630 (15767) | 15767..16626 | - | 860 | Protein_18 | IS3 family transposase | - |
QDX04_RS23635 (16740) | 16740..17135 | - | 396 | Protein_19 | ATP-binding protein | - |
QDX04_RS23640 (17483) | 17483..17857 | - | 375 | WP_015675362.1 | heat-labile enterotoxin LT subunit B | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | - | eltB / eltA | 1..112141 | 112141 | |
- | inside | IScluster/Tn | - | eltB / eltA | 2130..27610 | 25480 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A829CL36 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A2I6FMZ7 |