Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2180017..2180288 Replicon chromosome
Accession NZ_CP122719
Organism Escherichia coli strain ETEC1748

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2180147..2180250 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2180017..2180288 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDW92_RS10635 2176572..2177234 - 663 WP_000944256.1 exodeoxyribonuclease X -
QDW92_RS10640 2177258..2177914 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
QDW92_RS10645 2178016..2178246 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDW92_RS10650 2178385..2178759 + 375 WP_000204705.1 CopC domain-containing protein YobA -
QDW92_RS10655 2178763..2179635 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
QDW92_RS10660 2179648..2179989 + 342 WP_000976472.1 YebY family protein -
- 2180017..2180288 - 272 - - Antitoxin
- 2180147..2180250 + 104 - - Toxin
QDW92_RS10665 2180385..2181041 + 657 WP_001520704.1 protein-serine/threonine phosphatase -
QDW92_RS10670 2181042..2181233 - 192 WP_001296140.1 YebW family protein -
QDW92_RS10675 2181338..2181574 - 237 WP_001295499.1 YebV family protein -
QDW92_RS10680 2181692..2183131 - 1440 WP_024166480.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2156234..2196129 39895


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277756 NZ_CP122719:2180147-2180250 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277756 NZ_CP122719:c2180288-2180017 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References