Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2553436..2553707 Replicon chromosome
Accession NZ_CP122655
Organism Escherichia coli strain ETEC4074

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2553474..2553577 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2553436..2553707 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDW60_RS12735 2550593..2552032 + 1440 WP_024176540.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
QDW60_RS12740 2552150..2552386 + 237 WP_001295499.1 YebV family protein -
QDW60_RS12745 2552491..2552682 + 192 WP_001296140.1 YebW family protein -
QDW60_RS12750 2552683..2553339 - 657 WP_000812720.1 protein-serine/threonine phosphatase -
- 2553436..2553707 + 272 - - Antitoxin
- 2553474..2553577 - 104 - - Toxin
QDW60_RS12755 2553735..2554076 - 342 WP_000976476.1 YebY family protein -
QDW60_RS12760 2554089..2554961 - 873 WP_000879295.1 copper homeostasis membrane protein CopD -
QDW60_RS12765 2554965..2555339 - 375 WP_000168747.1 CopC domain-containing protein YobA -
QDW60_RS12770 2555478..2555708 + 231 WP_000916763.1 DNA polymerase III subunit theta -
QDW60_RS12775 2555810..2556466 + 657 WP_000011657.1 carbon-nitrogen hydrolase family protein YobB -
QDW60_RS12780 2556490..2557152 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277559 NZ_CP122655:c2553577-2553474 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277559 NZ_CP122655:2553436-2553707 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References