Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 2558045..2558580 Replicon chromosome
Accession NC_017857
Organism Methylophaga nitratireducenticrescens

Toxin (Protein)


Gene name parE Uniprot ID A0A7U5TVG9
Locus tag Q7A_RS12115 Protein ID WP_041354673.1
Coordinates 2558284..2558580 (+) Length 99 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A7U5TVF5
Locus tag Q7A_RS12110 Protein ID WP_041354672.1
Coordinates 2558045..2558284 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
- 2558045..2558284 + 240 - - Antitoxin

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-92)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11532.29 Da        Isoelectric Point: 8.4904

>T27752 WP_041354673.1 NC_017857:2558284-2558580 [Methylophaga nitratireducenticrescens]
MPSFKLSRKAKADLKSIALYTEREWGRDQRNHYILQFDHCFKLLVENPKLGQSCDEISLGYRQHLQGSHVIFYQQNAEGT
IEIIRILHKNMLPEGYLI

Download         Length: 297 bp

>T27752 NC_017857:2558284-2558580 [Methylophaga nitratireducenticrescens]
ATGCCAAGTTTCAAGCTTTCCAGGAAGGCCAAAGCTGATCTCAAATCTATAGCCCTTTACACGGAACGTGAATGGGGTCG
GGATCAACGAAACCACTACATTCTTCAGTTTGATCATTGCTTCAAGCTTTTGGTTGAGAATCCGAAGTTGGGGCAAAGCT
GCGATGAAATAAGTCTGGGTTATCGTCAACACCTTCAGGGCAGCCATGTTATTTTCTACCAACAGAACGCTGAAGGTACT
ATTGAGATTATCCGTATCCTCCACAAGAACATGTTGCCTGAAGGATATCTGATTTAG

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 9070.97 Da        Isoelectric Point: 4.8615

>AT27752 WP_041354672.1 NC_017857:2558045-2558284 [Methylophaga nitratireducenticrescens]
MHKNTSVSLGQHFDTFISEQLKSGRYSSTSEVVRAGLRLLEESETRLTTLRKLLKEGEDSGFEEYSYDAFIRELDNEGH

Download         Length: 240 bp

>AT27752 NC_017857:2558045-2558284 [Methylophaga nitratireducenticrescens]
ATGCATAAGAACACTAGCGTTAGTCTTGGCCAACATTTTGATACATTCATTTCTGAACAACTCAAAAGTGGCCGATACAG
CTCAACAAGTGAGGTTGTTCGTGCAGGATTGCGATTGCTTGAAGAGTCTGAAACTAGACTCACCACACTTCGAAAATTGC
TTAAAGAAGGCGAAGATAGTGGTTTCGAGGAATATTCCTATGATGCTTTTATTCGTGAACTGGATAATGAAGGACACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7U5TVG9

Antitoxin

Source ID Structure
AlphaFold DB A0A7U5TVF5

References