Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | V | Classification (family/domain) | ghoTS/ghoT-GhoS |
Location | 4623769..4624266 | Replicon | chromosome |
Accession | NZ_CP122648 | ||
Organism | Escherichia coli strain ETEC4077 |
Toxin (Protein)
Gene name | ghoT | Uniprot ID | L4JJG6 |
Locus tag | QDY56_RS22905 | Protein ID | WP_001173343.1 |
Coordinates | 4623769..4623942 (-) | Length | 58 a.a. |
Antitoxin (Protein)
Gene name | ghoS | Uniprot ID | L4JK92 |
Locus tag | QDY56_RS22910 | Protein ID | WP_000398619.1 |
Coordinates | 4623970..4624266 (-) | Length | 99 a.a. |
Genomic Context
Location: 4620439..4621896 (1458 bp)
Type: Others
Protein ID: WP_001550473.1
Type: Others
Protein ID: WP_001550473.1
Location: 4622133..4623650 (1518 bp)
Type: Others
Protein ID: WP_001295074.1
Type: Others
Protein ID: WP_001295074.1
Location: 4625187..4626818 (1632 bp)
Type: Others
Protein ID: WP_001216482.1
Type: Others
Protein ID: WP_001216482.1
Location: 4626815..4627534 (720 bp)
Type: Others
Protein ID: WP_000611288.1
Type: Others
Protein ID: WP_000611288.1
Location: 4623769..4623942 (174 bp)
Type: Toxin
Protein ID: WP_001173343.1
Type: Toxin
Protein ID: WP_001173343.1
Location: 4623970..4624266 (297 bp)
Type: Antitoxin
Protein ID: WP_000398619.1
Type: Antitoxin
Protein ID: WP_000398619.1
Location: 4624493..4624765 (273 bp)
Type: Others
Protein ID: WP_000405647.1
Type: Others
Protein ID: WP_000405647.1
Location: 4624777..4625007 (231 bp)
Type: Others
Protein ID: WP_001550470.1
Type: Others
Protein ID: WP_001550470.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
QDY56_RS22895 (4620439) | 4620439..4621896 | + | 1458 | WP_001550473.1 | dipeptide/tripeptide permease DtpC | - |
QDY56_RS22900 (4622133) | 4622133..4623650 | + | 1518 | WP_001295074.1 | lysine--tRNA ligase | - |
QDY56_RS22905 (4623769) | 4623769..4623942 | - | 174 | WP_001173343.1 | type V toxin-antitoxin system toxin GhoT | Toxin |
QDY56_RS22910 (4623970) | 4623970..4624266 | - | 297 | WP_000398619.1 | type V toxin-antitoxin system endoribonuclease antitoxin GhoS | Antitoxin |
QDY56_RS22915 (4624493) | 4624493..4624765 | - | 273 | WP_000405647.1 | GNAT family N-acetyltransferase | - |
QDY56_RS22920 (4624777) | 4624777..4625007 | - | 231 | WP_001550470.1 | 4Fe-4S mono-cluster protein YjdI | - |
QDY56_RS22925 (4625187) | 4625187..4626818 | + | 1632 | WP_001216482.1 | sensor histidine kinase | - |
QDY56_RS22930 (4626815) | 4626815..4627534 | + | 720 | WP_000611288.1 | two-component system response regulator DcuR | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | - | 4585070..4624266 | 39196 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Structures
Toxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9QI41 |
Antitoxin
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Source | ID | Structure |
---|---|---|
PDB | 2LLZ | |
AlphaFold DB | A0A7U9QBH6 |