Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 807401..807911 Replicon chromosome
Accession NC_017857
Organism Methylophaga nitratireducenticrescens

Toxin (Protein)


Gene name relB Uniprot ID I1XGX3
Locus tag Q7A_RS03820 Protein ID WP_014706017.1
Coordinates 807401..807664 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID I1XGX4
Locus tag Q7A_RS03825 Protein ID WP_014706018.1
Coordinates 807657..807911 (-) Length 85 a.a.

Genomic Context

Q7A_RS03800Q7A_RS03835Q7A_RS03795Q7A_RS03805Q7A_RS03810Q7A_RS03820Q7A_RS03825Q7A_RS03830Q7A_RS03840Q7A_RS03845
Location: 803820..805859 (2040 bp)
Type: Others
Protein ID: WP_041354334.1
Location: 809034..810518 (1485 bp)
Type: Others
Protein ID: WP_014706020.1
Location: 802886..803680 (795 bp)
Type: Others
Protein ID: WP_014706012.1
Location: 805948..806364 (417 bp)
Type: Others
Protein ID: WP_014706014.1
Location: 806624..806890 (267 bp)
Type: Others
Protein ID: WP_014706016.1
Location: 807401..807664 (264 bp)
Type: Toxin
Protein ID: WP_014706017.1
Location: 807657..807911 (255 bp)
Type: Antitoxin
Protein ID: WP_014706018.1
Location: 808548..808772 (225 bp)
Type: Others
Protein ID: WP_041354338.1
Location: 810507..810878 (372 bp)
Type: Others
Protein ID: WP_041354340.1
Location: 810939..812687 (1749 bp)
Type: Others
Protein ID: WP_014706022.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
Q7A_RS03795802886..803680-795WP_014706012.1UDP-2,3-diacylglucosamine diphosphatase-
Q7A_RS03800803820..805859+2040WP_041354334.1oligopeptidase A-
Q7A_RS03805805948..806364-417WP_014706014.1hypothetical protein-
Q7A_RS03810806624..806890-267WP_014706016.1DksA/TraR family C4-type zinc finger protein-
Q7A_RS03820807401..807664-264WP_014706017.1Txe/YoeB family addiction module toxinToxin
Q7A_RS03825807657..807911-255WP_014706018.1type II toxin-antitoxin system prevent-host-death family antitoxinAntitoxin
Q7A_RS03830808548..808772-225WP_041354338.1hypothetical protein-
Q7A_RS03835809034..810518+1485WP_014706020.14-hydroxy-3-polyprenylbenzoate decarboxylase-
Q7A_RS03840810507..810878-372WP_041354340.1MAPEG family protein-
Q7A_RS03845810939..812687-1749WP_014706022.1OFA family MFS transporter-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10408.85 Da        Isoelectric Point: 9.4084

>T27748 WP_014706017.1 NC_017857:c807664-807401 [Methylophaga nitratireducenticrescens]
MTKRLLSWTDEAWKDYLYWQGQDKKTLRRINKLITDVQRSPFEGIGKPEALKENLSGFWSRRIDDTHRLVYAVEDSAITI
VSCRYHY

Download         Length: 264 bp

>T27748 NC_017857:c807664-807401 [Methylophaga nitratireducenticrescens]
ATGACTAAACGCTTATTGTCATGGACTGACGAGGCTTGGAAAGATTATCTCTACTGGCAAGGTCAGGATAAAAAAACACT
ACGCCGAATCAACAAATTGATCACCGATGTTCAACGCAGTCCCTTTGAAGGGATCGGCAAACCGGAGGCCTTAAAAGAAA
ATCTATCCGGTTTCTGGTCGCGACGGATTGATGATACCCATCGCTTGGTTTATGCCGTTGAGGATTCAGCGATTACGATT
GTTTCTTGTCGGTATCATTATTAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9464.81 Da        Isoelectric Point: 5.6920

>AT27748 WP_014706018.1 NC_017857:c807911-807657 [Methylophaga nitratireducenticrescens]
MKIVSFSEARNSLKTVLDGVVNDADTTIITRRDAEDAVVMSLDYFNGLMETVHLLRSPENVKHLNKSIEQFKAGKAKPRE
LMDD

Download         Length: 255 bp

>AT27748 NC_017857:c807911-807657 [Methylophaga nitratireducenticrescens]
ATGAAAATCGTCTCATTTTCTGAAGCCAGAAATAGCTTAAAAACCGTTCTTGATGGTGTGGTGAACGATGCAGATACCAC
CATCATCACCCGCCGTGATGCAGAAGATGCCGTGGTGATGTCGTTGGATTACTTCAACGGCCTGATGGAAACCGTGCATT
TACTGCGCTCACCGGAGAACGTAAAACATCTGAATAAATCGATTGAACAATTCAAAGCTGGCAAGGCGAAACCGCGAGAG
CTGATGGATGACTAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBI1XGX3

Antitoxin

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Source
ID
Structure
AlphaFold DBI1XGX4

References