Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2210996..2211230 | Replicon | chromosome |
| Accession | NZ_CP122634 | ||
| Organism | Escherichia coli strain ETEC4085 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2211126..2211229 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2210996..2211230 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QDW62_RS10930 | 2207552..2208214 | - | 663 | WP_000944256.1 | exodeoxyribonuclease X | - |
| QDW62_RS10935 | 2208238..2208894 | - | 657 | WP_000011658.1 | carbon-nitrogen hydrolase family protein YobB | - |
| QDW62_RS10940 | 2208996..2209226 | - | 231 | WP_000916763.1 | DNA polymerase III subunit theta | - |
| QDW62_RS10945 | 2209365..2209739 | + | 375 | WP_000255065.1 | CopC domain-containing protein YobA | - |
| QDW62_RS10950 | 2209743..2210615 | + | 873 | WP_000879297.1 | copper homeostasis membrane protein CopD | - |
| QDW62_RS10955 | 2210628..2210969 | + | 342 | WP_000976472.1 | YebY family protein | - |
| - | 2210996..2211230 | - | 235 | - | - | Antitoxin |
| - | 2211126..2211229 | + | 104 | - | - | Toxin |
| QDW62_RS10960 | 2211360..2212436 | - | 1077 | WP_236294958.1 | phage integrase Arm DNA-binding domain-containing protein | - |
| QDW62_RS10965 | 2212402..2212683 | - | 282 | WP_001311878.1 | excisionase | - |
| QDW62_RS10970 | 2212790..2212978 | - | 189 | WP_021529595.1 | DUF1187 family protein | - |
| - | 2212794..2212972 | + | 179 | NuclAT_1 | - | - |
| - | 2212794..2212972 | + | 179 | NuclAT_1 | - | - |
| - | 2212794..2212972 | + | 179 | NuclAT_1 | - | - |
| - | 2212794..2212972 | + | 179 | NuclAT_1 | - | - |
| QDW62_RS10975 | 2212971..2213165 | - | 195 | WP_021500490.1 | type I toxin-antitoxin system endodeoxyribonuclease toxin RalR | - |
| QDW62_RS10980 | 2213229..2214317 | - | 1089 | WP_236294957.1 | RecT family recombinase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2205495..2275895 | 70400 | |
| - | inside | Genomic island | - | - | 2212402..2222323 | 9921 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 104 bp
>T277445 NZ_CP122634:2211126-2211229 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT
Antitoxin
Download Length: 235 bp
>AT277445 NZ_CP122634:c2211230-2210996 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGCGGTAGTCATCAGCTTAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT
