Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2073660..2073894 Replicon chromosome
Accession NZ_CP122620
Organism Escherichia coli strain ETEC4090

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2073790..2073893 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2073660..2073894 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDW69_RS10225 2070215..2070877 - 663 WP_000944256.1 exodeoxyribonuclease X -
QDW69_RS10230 2070901..2071557 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
QDW69_RS10235 2071659..2071889 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDW69_RS10240 2072028..2072402 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QDW69_RS10245 2072406..2073278 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
QDW69_RS10250 2073291..2073632 + 342 WP_000976476.1 YebY family protein -
- 2073660..2073894 - 235 - - Antitoxin
- 2073790..2073893 + 104 - - Toxin
QDW69_RS10255 2074025..2075101 - 1077 WP_053508942.1 phage integrase Arm DNA-binding domain-containing protein -
QDW69_RS10260 2075067..2075348 - 282 WP_077248935.1 excisionase -
QDW69_RS10265 2075455..2075643 - 189 WP_021529595.1 DUF1187 family protein -
- 2075459..2075637 + 179 NuclAT_5 - -
- 2075459..2075637 + 179 NuclAT_5 - -
- 2075459..2075637 + 179 NuclAT_5 - -
- 2075459..2075637 + 179 NuclAT_5 - -
QDW69_RS10270 2075636..2075830 - 195 WP_187182214.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
QDW69_RS10275 2075894..2076982 - 1089 WP_230905604.1 RecT family recombinase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1997902..2126330 128428


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277353 NZ_CP122620:2073790-2073893 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT277353 NZ_CP122620:c2073894-2073660 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References