Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2018165..2018436 Replicon chromosome
Accession NZ_CP122617
Organism Escherichia coli strain ETEC4091

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2018295..2018398 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2018165..2018436 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDW52_RS09725 2014720..2015382 - 663 WP_000944256.1 exodeoxyribonuclease X -
QDW52_RS09730 2015406..2016062 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
QDW52_RS09735 2016164..2016394 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QDW52_RS09740 2016533..2016907 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QDW52_RS09745 2016911..2017783 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
QDW52_RS09750 2017796..2018137 + 342 WP_000976472.1 YebY family protein -
- 2018165..2018436 - 272 - - Antitoxin
- 2018295..2018398 + 104 - - Toxin
QDW52_RS09755 2018533..2019189 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
QDW52_RS09760 2019190..2019381 - 192 WP_001296140.1 YebW family protein -
QDW52_RS09765 2019486..2019722 - 237 WP_001295499.1 YebV family protein -
QDW52_RS09770 2019840..2021279 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277330 NZ_CP122617:2018295-2018398 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277330 NZ_CP122617:c2018436-2018165 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References