Detailed information of TA system TA277293

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PanAT/DUF4065(antitoxin)
• Location: 4733428..4734353
• Replicon: chromosome
• Accession: NZ_CP122600
• Organism: Escherichia coli strain ETEC6333

Toxin (Protein)

• Gene name: panT
• Uniprot ID: -
• Locus tag: QDX83_RS23430
• Protein ID: WP_014640052.1
• Coordinates: 4733428..4733814 (-)
• Length: 129 a.a.

Antitoxin (Protein)

• Gene name: panA
• Uniprot ID: -
• Locus tag: QDX83_RS23435
• Protein ID: WP_024174200.1
• Coordinates: 4733844..4734353 (-)
• Length: 170 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	4686662..4739299	52637
	-	inside	Prophage	-	-	4686662..4739777	53115

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

• Antitoxin SocA-like, Panacea domain (6-116)

Sequences

Toxin

Protein

• Length: 129 a.a.
• Molecular weight: 14465.40 Da
• Isoelectric Point: 5.4833

>T277293 WP_014640052.1 NZ_CP122600:c4733814-4733428 [Escherichia coli]
VLAPTGPCNHLHVICNDPVYYPVNDCYCVLVVNISSIKDGVPHDPSCVLNSGDHRFIKHPSYVVYAEAIIWRVDNMVRKQ
RSGEISVHDDMPEATFNRILDGFDISDEVTPKNLKFKNKYCVSSIDDE

Nucleotide

• Length: 387 bp

Antitoxin

Protein

• Length: 170 a.a.
• Molecular weight: 19559.39 Da
• Isoelectric Point: 5.3338

>AT277293 WP_024174200.1 NZ_CP122600:c4734353-4733844 [Escherichia coli]
MAYLKLMKLLYLSNRKSILKHGRMIGEDSLYSMKFGPVMSNTLNLIRGKAEGIGDYWYNLIETNGHDVLLRSDPREMDAD
EVFDELSRADIRILDEIYSLYGHMNRFDLANMTHLESVCPEWHNPGNSRKPIDLKEMLISEGKSEDEANRIIGKMEESQK
LKEFSLQLS

Nucleotide

• Length: 510 bp