Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 579823..580406 | Replicon | chromosome |
Accession | NC_017845 | ||
Organism | Pectobacterium sp. SCC3193 |
Toxin (Protein)
Gene name | parE | Uniprot ID | A0A7V8QAI8 |
Locus tag | W5S_RS02600 | Protein ID | WP_012822278.1 |
Coordinates | 580101..580406 (+) | Length | 102 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7V8TMU0 |
Locus tag | W5S_RS02595 | Protein ID | WP_012822277.1 |
Coordinates | 579823..580113 (+) | Length | 97 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
W5S_RS02575 | 574925..576187 | - | 1263 | WP_012822274.1 | L-rhamnose isomerase | - |
W5S_RS02580 | 576184..577674 | - | 1491 | WP_014698651.1 | rhamnulokinase | - |
W5S_RS02585 | 578043..578882 | + | 840 | WP_005971146.1 | HTH-type transcriptional activator RhaS | - |
W5S_RS02590 | 578907..579761 | + | 855 | WP_012822276.1 | helix-turn-helix domain-containing protein | - |
W5S_RS02595 | 579823..580113 | + | 291 | WP_012822277.1 | ribbon-helix-helix protein, CopG family | Antitoxin |
W5S_RS02600 | 580101..580406 | + | 306 | WP_012822278.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
W5S_RS02605 | 580466..582154 | - | 1689 | WP_014698652.1 | ABC transporter ATP-binding protein | - |
W5S_RS02610 | 582151..583017 | - | 867 | WP_012822280.1 | ABC transporter permease | - |
W5S_RS02615 | 583010..583969 | - | 960 | WP_012822281.1 | ABC transporter permease | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 102 a.a. Molecular weight: 11634.48 Da Isoelectric Point: 9.4590
>T27728 WP_012822278.1 NC_017845:580101-580406 [Pectobacterium parmentieri]
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP
MPQVIVSERARRDLQRLQDFLKNKNALAAKKAAEVLIRGIRQLEALPNIGRPVEHLPLEYQELVIEFGSSGYVMLYRHDE
LTDRVVILTVKHQKEAGYQNP
Download Length: 306 bp
>T27728 NC_017845:580101-580406 [Pectobacterium parmentieri]
ATGCCACAAGTGATTGTTTCAGAACGCGCAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCCGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGCCATGATGAA
CTGACTGACAGAGTGGTGATCCTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA
ATGCCACAAGTGATTGTTTCAGAACGCGCAAGACGTGATTTGCAGCGTCTGCAGGATTTTCTAAAAAACAAAAATGCGCT
GGCTGCGAAAAAGGCCGCTGAAGTTTTGATTCGGGGCATTCGTCAGTTAGAAGCGCTGCCGAATATCGGGCGACCCGTTG
AACATCTCCCTCTTGAATATCAGGAACTGGTGATCGAATTCGGCAGCAGCGGGTACGTGATGCTTTACCGCCATGATGAA
CTGACTGACAGAGTGGTGATCCTGACCGTCAAGCATCAAAAAGAAGCCGGTTACCAAAACCCTTAA
Antitoxin
Download Length: 97 a.a. Molecular weight: 11097.16 Da Isoelectric Point: 4.7845
>AT27728 WP_012822277.1 NC_017845:579823-580113 [Pectobacterium parmentieri]
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK
MADTPRQTTTLRIDQDIKERLKTLADDRHSSAHALMLEAIAEYVEREEKRSQYRKEALAAWEEYQNTGEHITADETVTWL
ESWGSGHEQDAPACHK
Download Length: 291 bp
>AT27728 NC_017845:579823-580113 [Pectobacterium parmentieri]
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGCTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAACACCGGCGAACACATCACCGCCGATGAGACGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA
ATGGCTGACACGCCACGCCAAACCACGACGCTGCGCATCGATCAGGACATTAAAGAACGACTGAAAACGTTGGCCGATGA
CCGCCATAGCTCAGCCCATGCGCTAATGCTGGAAGCCATCGCCGAATACGTGGAGCGTGAAGAAAAACGCAGTCAGTACC
GTAAAGAGGCGCTGGCCGCGTGGGAGGAATACCAGAACACCGGCGAACACATCACCGCCGATGAGACGGTCACCTGGTTA
GAATCCTGGGGTTCTGGGCATGAACAGGATGCGCCTGCATGCCACAAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8QAI8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7V8TMU0 |