Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2079764..2079909 Replicon chromosome
Accession NZ_CP122587
Organism Klebsiella pneumoniae strain NCRE-61

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2079800..2079902 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2079764..2079909 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDV36_RS14405 (QDV36_14410) 2074894..2076954 + 2061 WP_004151449.1 oligopeptidase B -
QDV36_RS14410 (QDV36_14415) 2076958..2077617 - 660 WP_002911407.1 exodeoxyribonuclease X -
QDV36_RS14415 (QDV36_14420) 2077696..2077926 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QDV36_RS14420 (QDV36_14425) 2078039..2078413 + 375 WP_039819395.1 CopC domain-containing protein YobA -
QDV36_RS14425 (QDV36_14430) 2078417..2079286 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
QDV36_RS14430 (QDV36_14435) 2079303..2079641 + 339 WP_002911404.1 YebY family protein -
- 2079764..2079909 - 146 - - Antitoxin
- 2079800..2079902 + 103 - - Toxin
QDV36_RS14435 (QDV36_14440) 2080278..2080421 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
QDV36_RS14440 (QDV36_14445) 2080526..2081494 - 969 WP_014907334.1 VirK/YbjX family protein -
QDV36_RS14445 (QDV36_14450) 2081651..2082304 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
QDV36_RS14450 (QDV36_14455) 2082301..2082492 - 192 WP_002911395.1 YebW family protein -
QDV36_RS14455 (QDV36_14460) 2082590..2082829 - 240 WP_002911393.1 YebV family protein -
QDV36_RS14460 (QDV36_14465) 2082945..2084378 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T277223 NZ_CP122587:2079800-2079902 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT277223 NZ_CP122587:c2079909-2079764 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References