Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1911435..1911580 Replicon chromosome
Accession NZ_CP122578
Organism Klebsiella pneumoniae strain KP-2683-1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1911471..1911573 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1911435..1911580 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDV38_RS12025 1906565..1908625 + 2061 WP_279956715.1 oligopeptidase B -
QDV38_RS12030 1908629..1909288 - 660 WP_002911407.1 exodeoxyribonuclease X -
QDV38_RS12035 1909367..1909597 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QDV38_RS12040 1909710..1910084 + 375 WP_004151448.1 CopC domain-containing protein YobA -
QDV38_RS12045 1910088..1910957 + 870 WP_014907333.1 copper homeostasis membrane protein CopD -
QDV38_RS12050 1910974..1911312 + 339 WP_002911404.1 YebY family protein -
- 1911435..1911580 - 146 - - Antitoxin
- 1911471..1911573 + 103 - - Toxin
QDV38_RS12055 1911948..1912091 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
QDV38_RS12060 1912196..1913164 - 969 WP_014907334.1 VirK/YbjX family protein -
QDV38_RS12065 1913321..1913974 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
QDV38_RS12070 1913971..1914162 - 192 WP_002911395.1 YebW family protein -
QDV38_RS12075 1914260..1914499 - 240 WP_002911393.1 YebV family protein -
QDV38_RS12080 1914615..1916048 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T277204 NZ_CP122578:1911471-1911573 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT277204 NZ_CP122578:c1911580-1911435 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References