277186

Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1985187..1985332 Replicon chromosome
Accession NZ_CP122573
Organism Klebsiella pneumoniae strain KP2185

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1985223..1985325 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1985187..1985332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDV37_RS13650 (QDV37_13660) 1980317..1982377 + 2061 WP_004151449.1 oligopeptidase B -
QDV37_RS13655 (QDV37_13665) 1982381..1983040 - 660 WP_002911407.1 exodeoxyribonuclease X -
QDV37_RS13660 (QDV37_13670) 1983119..1983349 - 231 WP_002911406.1 DNA polymerase III subunit theta -
QDV37_RS13665 (QDV37_13675) 1983462..1983836 + 375 WP_039819395.1 CopC domain-containing protein YobA -
QDV37_RS13670 (QDV37_13680) 1983840..1984709 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
QDV37_RS13675 (QDV37_13685) 1984726..1985064 + 339 WP_002911404.1 YebY family protein -
- 1985187..1985332 - 146 - - Antitoxin
- 1985223..1985325 + 103 - - Toxin
QDV37_RS13680 (QDV37_13690) 1985701..1985844 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
QDV37_RS13685 (QDV37_13695) 1985949..1986917 - 969 WP_014907334.1 VirK/YbjX family protein -
QDV37_RS13690 (QDV37_13700) 1987074..1987727 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
QDV37_RS13695 (QDV37_13705) 1987724..1987915 - 192 WP_002911395.1 YebW family protein -
QDV37_RS13700 (QDV37_13710) 1988013..1988252 - 240 WP_002911393.1 YebV family protein -
QDV37_RS13705 (QDV37_13715) 1988368..1989801 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T277186 NZ_CP122573:1985223-1985325 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT277186 NZ_CP122573:c1985332-1985187 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References