Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2855336..2855991 Replicon chromosome
Accession NZ_CP122566
Organism Auritidibacter ignavus strain BABAE-6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX21_RS13175 Protein ID WP_110100005.1
Coordinates 2855566..2855991 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX21_RS13170 Protein ID WP_110100006.1
Coordinates 2855336..2855569 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX21_RS13160 (QDX21_13160) 2851601..2853808 - 2208 WP_279674872.1 choline BCCT transporter BetT -
QDX21_RS13165 (QDX21_13165) 2854103..2855188 + 1086 WP_279674873.1 redox-regulated ATPase YchF -
QDX21_RS13170 (QDX21_13170) 2855336..2855569 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX21_RS13175 (QDX21_13175) 2855566..2855991 + 426 WP_110100005.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX21_RS13180 (QDX21_13180) 2856004..2856540 + 537 WP_158278495.1 GNAT family N-acetyltransferase -
QDX21_RS13185 (QDX21_13185) 2857084..2857809 + 726 WP_110100002.1 hypothetical protein -
QDX21_RS13190 (QDX21_13190) 2858034..2858267 + 234 Protein_2580 type II toxin-antitoxin system RelE/ParE family toxin -
QDX21_RS13195 (QDX21_13195) 2858273..2858578 + 306 WP_279675474.1 helix-turn-helix transcriptional regulator -
QDX21_RS13200 (QDX21_13200) 2858729..2858962 + 234 WP_279674874.1 hypothetical protein -
QDX21_RS13205 (QDX21_13205) 2858947..2859321 + 375 WP_279674875.1 hypothetical protein -
QDX21_RS13210 (QDX21_13210) 2859587..2860351 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15267.47 Da        Isoelectric Point: 5.2123

>T277175 WP_110100005.1 NZ_CP122566:2855566-2855991 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQIAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277175 WP_110100006.1 NZ_CP122566:2855336-2855569 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References