Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 26733..27388 Replicon chromosome
Accession NZ_CP122565
Organism Auritidibacter ignavus strain BABAE-5

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX23_RS00135 Protein ID WP_110100194.1
Coordinates 26963..27388 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX23_RS00130 Protein ID WP_110100006.1
Coordinates 26733..26966 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX23_RS00120 (QDX23_00120) 22998..25205 - 2208 WP_110100192.1 choline BCCT transporter BetT -
QDX23_RS00125 (QDX23_00125) 25500..26585 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
QDX23_RS00130 (QDX23_00130) 26733..26966 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX23_RS00135 (QDX23_00135) 26963..27388 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX23_RS00140 (QDX23_00140) 27401..27937 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX23_RS00145 (QDX23_00145) 28481..29206 + 726 WP_110100197.1 hypothetical protein -
QDX23_RS00150 (QDX23_00150) 29473..29664 + 192 WP_233487799.1 type II toxin-antitoxin system RelE/ParE family toxin -
QDX23_RS00155 (QDX23_00155) 29670..29975 + 306 WP_110100392.1 helix-turn-helix transcriptional regulator -
QDX23_RS00160 (QDX23_00160) 30344..30718 + 375 WP_146206389.1 hypothetical protein -
QDX23_RS00165 (QDX23_00165) 30984..31748 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15255.42 Da        Isoelectric Point: 5.2123

>T277173 WP_110100194.1 NZ_CP122565:26963-27388 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQTAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277173 WP_110100006.1 NZ_CP122565:26733-26966 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References