Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2634700..2635355 Replicon chromosome
Accession NZ_CP122564
Organism Auritidibacter ignavus strain BABAE-4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX22_RS11960 Protein ID WP_110100194.1
Coordinates 2634930..2635355 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX22_RS11955 Protein ID WP_110100006.1
Coordinates 2634700..2634933 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX22_RS11945 (QDX22_11945) 2630965..2633172 - 2208 WP_110100192.1 choline BCCT transporter BetT -
QDX22_RS11950 (QDX22_11950) 2633467..2634552 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
QDX22_RS11955 (QDX22_11955) 2634700..2634933 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX22_RS11960 (QDX22_11960) 2634930..2635355 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX22_RS11965 (QDX22_11965) 2635368..2635904 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX22_RS11970 (QDX22_11970) 2636050..2636250 - 201 WP_110100196.1 hypothetical protein -
QDX22_RS11975 (QDX22_11975) 2636448..2637173 + 726 WP_110100197.1 hypothetical protein -
QDX22_RS11980 (QDX22_11980) 2637398..2637631 + 234 Protein_2338 type II toxin-antitoxin system RelE/ParE family toxin -
QDX22_RS11985 (QDX22_11985) 2637637..2637942 + 306 WP_110100392.1 helix-turn-helix transcriptional regulator -
QDX22_RS11990 (QDX22_11990) 2638093..2638326 + 234 WP_110100198.1 hypothetical protein -
QDX22_RS11995 (QDX22_11995) 2638587..2638892 + 306 WP_146206324.1 hypothetical protein -
QDX22_RS12000 (QDX22_12000) 2638951..2639715 + 765 WP_110099999.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15255.42 Da        Isoelectric Point: 5.2123

>T277172 WP_110100194.1 NZ_CP122564:2634930-2635355 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQTAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277172 WP_110100006.1 NZ_CP122564:2634700-2634933 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References