Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2634240..2634895 Replicon chromosome
Accession NZ_CP122563
Organism Auritidibacter ignavus strain BABAE-3

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX24_RS11960 Protein ID WP_110100194.1
Coordinates 2634470..2634895 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX24_RS11955 Protein ID WP_110100006.1
Coordinates 2634240..2634473 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX24_RS11945 (QDX24_11945) 2630505..2632712 - 2208 WP_110100192.1 choline BCCT transporter BetT -
QDX24_RS11950 (QDX24_11950) 2633007..2634092 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
QDX24_RS11955 (QDX24_11955) 2634240..2634473 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX24_RS11960 (QDX24_11960) 2634470..2634895 + 426 WP_110100194.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX24_RS11965 (QDX24_11965) 2634908..2635444 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX24_RS11970 (QDX24_11970) 2635590..2635790 - 201 WP_110100196.1 hypothetical protein -
QDX24_RS11975 (QDX24_11975) 2635988..2636713 + 726 WP_110100197.1 hypothetical protein -
QDX24_RS11980 (QDX24_11980) 2636938..2637171 + 234 Protein_2338 type II toxin-antitoxin system RelE/ParE family toxin -
QDX24_RS11985 (QDX24_11985) 2637177..2637482 + 306 WP_110100392.1 helix-turn-helix transcriptional regulator -
QDX24_RS11990 (QDX24_11990) 2637633..2637866 + 234 WP_110100198.1 hypothetical protein -
QDX24_RS11995 (QDX24_11995) 2638127..2638432 + 306 WP_146206324.1 hypothetical protein -
QDX24_RS12000 (QDX24_12000) 2638491..2639255 + 765 WP_110099999.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15255.42 Da        Isoelectric Point: 5.2123

>T277171 WP_110100194.1 NZ_CP122563:2634470-2634895 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQTAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277171 WP_110100006.1 NZ_CP122563:2634240-2634473 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References