Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 2593923..2594578 Replicon chromosome
Accession NZ_CP122562
Organism Auritidibacter ignavus strain BABAE-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX20_RS11670 Protein ID WP_110100005.1
Coordinates 2594153..2594578 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX20_RS11665 Protein ID WP_110100006.1
Coordinates 2593923..2594156 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX20_RS11655 (QDX20_11655) 2590188..2592395 - 2208 WP_110100192.1 choline BCCT transporter BetT -
QDX20_RS11660 (QDX20_11660) 2592690..2593775 + 1086 WP_279673607.1 redox-regulated ATPase YchF -
QDX20_RS11665 (QDX20_11665) 2593923..2594156 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX20_RS11670 (QDX20_11670) 2594153..2594578 + 426 WP_110100005.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX20_RS11675 (QDX20_11675) 2594591..2595127 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX20_RS11680 (QDX20_11680) 2595671..2596396 + 726 WP_279673608.1 hypothetical protein -
QDX20_RS11685 (QDX20_11685) 2596427..2597590 - 1164 WP_279673098.1 IS30 family transposase -
QDX20_RS11690 (QDX20_11690) 2597850..2598083 + 234 Protein_2281 type II toxin-antitoxin system RelE/ParE family toxin -
QDX20_RS11695 (QDX20_11695) 2598089..2598394 + 306 WP_279673609.1 helix-turn-helix transcriptional regulator -
QDX20_RS11700 (QDX20_11700) 2599039..2599344 + 306 WP_146206324.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15267.47 Da        Isoelectric Point: 5.2123

>T277170 WP_110100005.1 NZ_CP122562:2594153-2594578 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAPISTADAQIAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277170 WP_110100006.1 NZ_CP122562:2593923-2594156 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References