Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 29121..29776 Replicon chromosome
Accession NZ_CP122561
Organism Auritidibacter ignavus strain BABAE-1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag QDX25_RS00140 Protein ID WP_279672825.1
Coordinates 29351..29776 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag QDX25_RS00135 Protein ID WP_110100006.1
Coordinates 29121..29354 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QDX25_RS00125 (QDX25_00125) 25386..27593 - 2208 WP_110100192.1 choline BCCT transporter BetT -
QDX25_RS00130 (QDX25_00130) 27888..28973 + 1086 WP_110100193.1 redox-regulated ATPase YchF -
QDX25_RS00135 (QDX25_00135) 29121..29354 + 234 WP_110100006.1 Arc family DNA-binding protein Antitoxin
QDX25_RS00140 (QDX25_00140) 29351..29776 + 426 WP_279672825.1 type II toxin-antitoxin system VapC family toxin Toxin
QDX25_RS00145 (QDX25_00145) 29789..30325 + 537 WP_158524689.1 GNAT family N-acetyltransferase -
QDX25_RS00150 (QDX25_00150) 30471..30671 - 201 WP_110100196.1 hypothetical protein -
QDX25_RS00155 (QDX25_00155) 30869..31594 + 726 WP_110100197.1 hypothetical protein -
QDX25_RS00160 (QDX25_00160) 31819..32052 + 234 Protein_31 type II toxin-antitoxin system RelE/ParE family toxin -
QDX25_RS00165 (QDX25_00165) 32058..32363 + 306 WP_110100392.1 helix-turn-helix transcriptional regulator -
QDX25_RS00170 (QDX25_00170) 32732..33106 + 375 WP_146206389.1 hypothetical protein -
QDX25_RS00175 (QDX25_00175) 33372..34136 + 765 WP_110100200.1 sulfite exporter TauE/SafE family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-128)

Antitoxin

Arc-like DNA binding domain

(13-40)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15286.43 Da        Isoelectric Point: 5.2123

>T277169 WP_279672825.1 NZ_CP122561:29351-29776 [Auritidibacter ignavus]
VIILDTNVISEIFRPLPEPRVADWLTSLEGDVAITSVTLAELLAGLRRLPDGRRRDALTRRIDVALAPYRGGRAVLPFDD
VAADRYADVLVARERAGAQISTADAQTAAICLAHGATCATRNVKDFQHTGVELVDPWKVDA

Download         Length: 426 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8242.47 Da        Isoelectric Point: 5.6643

>AT277169 WP_110100006.1 NZ_CP122561:29121-29354 [Auritidibacter ignavus]
MSSIIVRGLDDAVKQQLAAQAKEHGRSMEAEVRAILTKAARRPHIGIALLAAAQDVGGVEELPIPVRDDVARAVDFE

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References