Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2014618..2014889 Replicon chromosome
Accession NZ_CP122517
Organism Escherichia coli strain MY1-8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2014748..2014851 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2014618..2014889 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCL60_RS09660 2011173..2011835 - 663 WP_000944256.1 exodeoxyribonuclease X -
QCL60_RS09665 2011859..2012515 - 657 WP_000011652.1 carbon-nitrogen hydrolase family protein YobB -
QCL60_RS09670 2012617..2012847 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QCL60_RS09675 2012986..2013360 + 375 WP_000204699.1 CopC domain-containing protein YobA -
QCL60_RS09680 2013364..2014236 + 873 WP_000879282.1 copper homeostasis membrane protein CopD -
QCL60_RS09685 2014249..2014590 + 342 WP_000976472.1 YebY family protein -
- 2014618..2014889 - 272 - - Antitoxin
- 2014748..2014851 + 104 - - Toxin
QCL60_RS09690 2015040..2015642 + 603 WP_247856325.1 protein-serine/threonine phosphatase -
QCL60_RS09695 2015643..2015834 - 192 WP_001296140.1 YebW family protein -
QCL60_RS09700 2015939..2016175 - 237 WP_001295499.1 YebV family protein -
QCL60_RS09705 2016293..2017732 - 1440 WP_001307251.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277142 NZ_CP122517:2014748-2014851 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277142 NZ_CP122517:c2014889-2014618 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References