277134

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 1330643..1331216 Replicon chromosome
Accession NZ_CP122516
Organism Helicobacter pylori strain HP34

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag QCM40_RS06460 Protein ID WP_279954808.1
Coordinates 1330643..1330915 (-) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag QCM40_RS06465 Protein ID WP_121092335.1
Coordinates 1330929..1331216 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCM40_RS06440 (QCM40_06440) 1327290..1328057 - 768 WP_000242349.1 ABC transporter ATP-binding protein -
QCM40_RS06445 (QCM40_06445) 1328057..1329037 - 981 WP_000921452.1 iron ABC transporter permease -
QCM40_RS06450 (QCM40_06450) 1329030..1329872 - 843 WP_279954805.1 SDR family oxidoreductase -
QCM40_RS06455 (QCM40_06455) 1330012..1330536 + 525 WP_279954806.1 acyl-CoA thioesterase -
QCM40_RS06460 (QCM40_06460) 1330643..1330915 - 273 WP_279954808.1 type II toxin-antitoxin system YafQ family toxin Toxin
QCM40_RS06465 (QCM40_06465) 1330929..1331216 - 288 WP_121092335.1 type II toxin-antitoxin system antitoxin Antitoxin
QCM40_RS06470 (QCM40_06470) 1332012..1334225 - 2214 WP_279954812.1 outer membrane beta-barrel protein -
QCM40_RS06475 (QCM40_06475) 1334298..1334479 + 182 Protein_1265 hypothetical protein -
QCM40_RS06490 (QCM40_06490) 1334914..1335444 + 531 WP_279954813.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10538.60 Da        Isoelectric Point: 10.2671

>T277134 WP_279954808.1 NZ_CP122516:c1330915-1330643 [Helicobacter pylori]
MLTIETSKKFDKNLKILVKNGFDLKLLYKVVENLAKEQPLAPKYKDYPFKGGLKDFRECHLKPDLLLVYQIKKPKNTLFL
VRLGSHSELF

Download         Length: 273 bp

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11394.14 Da        Isoelectric Point: 10.3368

>AT277134 WP_121092335.1 NZ_CP122516:c1331216-1330929 [Helicobacter pylori]
MPNTTNKDYTKYSQRQLFNFLNSIKTKQKRALEKLKEIQTQKQRIKKALQFKALNLTENGYTIEEEREILARAKDTKNHL
CFKSIEDFKKHCENL

Download         Length: 288 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References