Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PanAT/DUF4065(antitoxin)
Location 581599..582790 Replicon chromosome
Accession NZ_CP122515
Organism Helicobacter pylori strain HP22

Toxin (Protein)


Gene name panT Uniprot ID -
Locus tag QCM05_RS02830 Protein ID WP_140446210.1
Coordinates 582026..582790 (+) Length 255 a.a.

Antitoxin (Protein)


Gene name panA Uniprot ID -
Locus tag QCM05_RS02825 Protein ID WP_120824146.1
Coordinates 581599..582036 (+) Length 146 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QCM05_RS02815 (QCM05_02815) 580318..580797 + 480 WP_279963382.1 reverse transcriptase domain-containing protein -
QCM05_RS02820 (QCM05_02820) 580855..581373 + 519 WP_001869765.1 hypothetical protein -
QCM05_RS02825 (QCM05_02825) 581599..582036 + 438 WP_120824146.1 Panacea domain-containing protein Antitoxin
QCM05_RS02830 (QCM05_02830) 582026..582790 + 765 WP_140446210.1 hypothetical protein Toxin
QCM05_RS02835 (QCM05_02835) 583015..584202 - 1188 WP_279963384.1 transcription termination factor NusA -
QCM05_RS02840 (QCM05_02840) 584290..585450 - 1161 WP_279963385.1 aminotransferase class V-fold PLP-dependent enzyme -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Antitoxin SocA-like, Panacea domain

(24-119)


Sequences

Toxin        


Download         Length: 255 a.a.        Molecular weight: 29805.00 Da        Isoelectric Point: 8.8819

>T277132 WP_140446210.1 NZ_CP122515:582026-582790 [Helicobacter pylori]
MEIKEEDKDKKLEKIIVLLCEKGDLSSQKDQIIKDLKEIYKGEYKHKYSKITTIILNSTRDKEQAFMMLTQNIKTLKEIQ
DNKEVESIKPKLEKLYDHMNLECIRLQDFDEKMSRVKDVSIKLEDELNKNYKKLSEELNKQQTQYITILGIFASIVLTFV
GGLAFSTSVLSNIDKANAYRLVFVMAFIALFFGNILYLLFSFLSKISLSEEKKDKQENFFKKPIFWFNLIVTILFVIGFC
GELHIIQRLASKYF

Download         Length: 765 bp

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 17300.42 Da        Isoelectric Point: 6.1265

>AT277132 WP_120824146.1 NZ_CP122515:581599-582036 [Helicobacter pylori]
MVNTLELAKYILKHSNKELSNLELQKTLYFTELDYIKKFDKHLVSDDFEAWKYGPVAREVYYEYRNYGANSIDKPKEETL
SQDLREDELETINRSIKKCNEKSYWDLVKESHKEDGAWHKSFKEDRKEIISKDLIKQEAKQANGN

Download         Length: 438 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References