Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2020055..2020326 Replicon chromosome
Accession NZ_CP122507
Organism Escherichia coli strain W444

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2020185..2020288 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2020055..2020326 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
QC806_RS09930 2016611..2017273 - 663 WP_000944249.1 exodeoxyribonuclease X -
QC806_RS09935 2017296..2017952 - 657 WP_021577595.1 carbon-nitrogen hydrolase family protein YobB -
QC806_RS09940 2018054..2018284 - 231 WP_000916763.1 DNA polymerase III subunit theta -
QC806_RS09945 2018423..2018797 + 375 WP_000168747.1 CopC domain-containing protein YobA -
QC806_RS09950 2018801..2019673 + 873 WP_284632160.1 copper homeostasis membrane protein CopD -
QC806_RS09955 2019686..2020027 + 342 WP_000976472.1 YebY family protein -
- 2020055..2020326 - 272 - - Antitoxin
- 2020185..2020288 + 104 - - Toxin
QC806_RS09960 2020423..2021079 + 657 WP_000812739.1 protein-serine/threonine phosphatase -
QC806_RS09965 2021080..2021271 - 192 WP_001313035.1 YebW family protein -
QC806_RS09970 2021376..2021612 - 237 WP_001295499.1 YebV family protein -
QC806_RS09975 2021730..2023169 - 1440 WP_096320361.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T277103 NZ_CP122507:2020185-2020288 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT277103 NZ_CP122507:c2020326-2020055 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References