Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1806997..1807142 Replicon chromosome
Accession NZ_CP122469
Organism Klebsiella pneumoniae subsp. pneumoniae strain IITJ_BC16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1807033..1807135 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1806997..1807142 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9M40_RS08765 1802127..1804187 + 2061 WP_004151449.1 oligopeptidase B -
P9M40_RS08770 1804191..1804850 - 660 WP_002911407.1 exodeoxyribonuclease X -
P9M40_RS08775 1804929..1805159 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P9M40_RS08780 1805272..1805646 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P9M40_RS08785 1805650..1806519 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
P9M40_RS08790 1806536..1806874 + 339 WP_009307539.1 YebY family protein -
- 1806997..1807142 - 146 - - Antitoxin
- 1807033..1807135 + 103 - - Toxin
P9M40_RS08795 1807511..1807654 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P9M40_RS08800 1807759..1808727 - 969 WP_004151446.1 VirK/YbjX family protein -
P9M40_RS08805 1808884..1809537 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
P9M40_RS08810 1809534..1809725 - 192 WP_002911395.1 YebW family protein -
P9M40_RS08815 1809823..1810062 - 240 WP_002911393.1 YebV family protein -
P9M40_RS08820 1810178..1811611 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T276980 NZ_CP122469:1807033-1807135 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT276980 NZ_CP122469:c1807142-1806997 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References