Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1807164..1807309 Replicon chromosome
Accession NZ_CP122461
Organism Klebsiella pneumoniae subsp. pneumoniae strain IITJ_U23

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1807200..1807302 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1807164..1807309 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
P9M41_RS08770 1802294..1804354 + 2061 WP_004151449.1 oligopeptidase B -
P9M41_RS08775 1804358..1805017 - 660 WP_002911407.1 exodeoxyribonuclease X -
P9M41_RS08780 1805096..1805326 - 231 WP_002911406.1 DNA polymerase III subunit theta -
P9M41_RS08785 1805439..1805813 + 375 WP_004151448.1 CopC domain-containing protein YobA -
P9M41_RS08790 1805817..1806686 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
P9M41_RS08795 1806703..1807041 + 339 WP_009307539.1 YebY family protein -
- 1807164..1807309 - 146 - - Antitoxin
- 1807200..1807302 + 103 - - Toxin
P9M41_RS08800 1807678..1807821 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
P9M41_RS08805 1807926..1808894 - 969 WP_004151446.1 VirK/YbjX family protein -
P9M41_RS08810 1809051..1809704 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
P9M41_RS08815 1809701..1809892 - 192 WP_002911395.1 YebW family protein -
P9M41_RS08820 1809990..1810229 - 240 WP_002911393.1 YebV family protein -
P9M41_RS08825 1810345..1811778 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T276965 NZ_CP122461:1807200-1807302 [Klebsiella pneumoniae subsp. pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT276965 NZ_CP122461:c1807309-1807164 [Klebsiella pneumoniae subsp. pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References